[3dem] Funded Postdoc Position Open for in situ CryoET of Malaria Parasites in the Ho Lab at Columbia University in New York City!

[Ho, Chi-Min]

Dear Colleagues,

The Ho Lab at Columbia University is seeking talented and motivated postdoctoral research scholars to join us in using in situ cryo electron tomography (CryoET) and single particle cryo electron microscopy (CryoEM) to explore how membrane protein complexes mediate host-pathogen interactions in the Malaria parasite Plasmodium falciparum. Projects will be focused on using cryoFIB milling and cryoET to directly visualize the host-pathogen interface in parasite-infected human red blood cells, as well as single-particle cryoEM structure determination of native membrane protein complexes purified directly from Malaria parasites. Our lab is located in the Department of Microbiology & Immunology at Columbia University Irving Medical Center in New York City, New York. More information here: https://urldefense.com/v3/__http://www.cmholab.org/research__;!!Mih3wA!F1ZPTn8nUXj34DFbA8PdYpusVM3Gduw7beN8hhIpNaI_xF-VEEvRxCbAyfb6xsx80bWNc2zPA_7CI-Lrjs5Fvx5kJQ$ <https://urldefense.com/v3/__http://www.cmholab.org/research__;!!Mih3wA!F1ZPTn8nUXj34DFbA8PdYpusVM3Gduw7beN8hhIpNaI_xF-VEEvRxCbAyfb6xsx80bWNc2zPA_7CI-Lrjs5Fvx5kJQ$ >.

If interested, please send a cover letter, CV, and contact information for three references to Dr. Chi-Min Ho at ch3516 at cumc.columbia.edu<mailto:ch3516 at cumc.columbia.edu>.

We are looking for innovative, resourceful and resilient scientists who enjoy learning new things, meeting new people, and being part of an open, collaborative team. Successful candidates will join a vibrant, collaborative research community and enjoy access to the state-of-the-art electron microscopy facilities at Columbia, including:

*         Multiple Titan Krios microscopes with a Gatan BioQuantum energy filter and Gatan K3 direct electron detector

*         A dual-beam Aquilos cryo-FIB/SEM microscope, Leica cryo-correlative fluorescence light microscope

*         A Glacios screening microscope with a Gatan K3 direct electron detector
Salary and benefits are competitive based on experience.
________________________________
Qualifications

*         A PhD in biophysics, structural biology, materials science, physics, or molecular parasitology.

*         A strong background and proven track record in one of more of the following areas: molecular parasitology of malaria parasites, single particle cryoEM, cryoET, cryoFIB-SEM milling.

*         Experience with Python and/or MATLAB is a plus.

*         Strong communication, interpersonal and organizational skills, and excellent attention to detail.


[cid:image003.jpg at 01DAAB3F.87F65C90]
Anton et al, bioRxiv 2023, doi: https://urldefense.com/v3/__https://doi.org/10.1101/2023.09.03.556115__;!!Mih3wA!F1ZPTn8nUXj34DFbA8PdYpusVM3Gduw7beN8hhIpNaI_xF-VEEvRxCbAyfb6xsx80bWNc2zPA_7CI-Lrjs4YIu0piw$ 


Chi-Min Ho
Assistant Professor of Microbiology & Immunology
Columbia University, Vagelos College of Physicians & Surgeons

Columbia University Irving Medical Center
701 West 168th Street
Hammer Health Sciences Center
New York, NY 10032
https://urldefense.com/v3/__http://www.cmholab.org__;!!Mih3wA!F1ZPTn8nUXj34DFbA8PdYpusVM3Gduw7beN8hhIpNaI_xF-VEEvRxCbAyfb6xsx80bWNc2zPA_7CI-Lrjs5QAZp-IA$ <https://urldefense.com/v3/__http://www.cmholab.org/__;!!Mih3wA!F1ZPTn8nUXj34DFbA8PdYpusVM3Gduw7beN8hhIpNaI_xF-VEEvRxCbAyfb6xsx80bWNc2zPA_7CI-Lrjs54aJXlaQ$ >

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