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<p class="MsoNormal">Dear Colleagues, <o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><span style="font-size:12.0pt">The Ho Lab at Columbia University is seeking talented and motivated postdoctoral research scholars to join us in using in situ cryo electron tomography (CryoET) and single particle cryo electron microscopy
(CryoEM) to explore how membrane protein complexes mediate host-pathogen interactions in the Malaria parasite
<i>Plasmodium falciparum</i>.</span> <span style="font-size:12.0pt">Projects will be focused on using cryoFIB milling and cryoET to directly visualize the host-pathogen interface in parasite-infected human red blood cells, as well as single-particle cryoEM
structure determination of native membrane protein complexes purified directly from Malaria parasites. Our lab is located in the Department of Microbiology & Immunology at Columbia University Irving Medical Center in New York City, New York. More information
here: </span><a href="https://urldefense.com/v3/__http://www.cmholab.org/research__;!!Mih3wA!F1ZPTn8nUXj34DFbA8PdYpusVM3Gduw7beN8hhIpNaI_xF-VEEvRxCbAyfb6xsx80bWNc2zPA_7CI-Lrjs5Fvx5kJQ$"><span style="font-size:12.0pt">www.cmholab.org/research</span></a><span style="font-size:12.0pt">.
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt">If interested, please send a cover letter, CV, and contact information for three references to Dr. Chi-Min Ho at
</span><a href="mailto:ch3516@cumc.columbia.edu"><span style="font-size:12.0pt">ch3516@cumc.columbia.edu</span></a><span style="font-size:12.0pt">.
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:4.0pt"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt">We are looking for innovative, resourceful and resilient scientists who enjoy learning new things, meeting new people, and being part of an open, collaborative team. Successful candidates will join a vibrant,
collaborative research community and enjoy access to the state-of-the-art electron microscopy facilities at Columbia, including:
<o:p></o:p></span></p>
<p class="MsoListParagraphCxSpFirst" style="text-indent:-.25in;mso-list:l3 level1 lfo1">
<![if !supportLists]><span style="font-size:12.0pt;line-height:106%;font-family:Symbol"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span style="font-size:12.0pt;line-height:106%">Multiple Titan Krios microscopes with a Gatan BioQuantum energy filter and Gatan K3 direct electron detector<o:p></o:p></span></p>
<p class="MsoListParagraphCxSpMiddle" style="text-indent:-.25in;mso-list:l3 level1 lfo1">
<![if !supportLists]><span style="font-size:12.0pt;line-height:106%;font-family:Symbol"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span style="font-size:12.0pt;line-height:106%">A dual-beam Aquilos cryo-FIB/SEM microscope, Leica cryo-correlative fluorescence light microscope<o:p></o:p></span></p>
<p class="MsoListParagraphCxSpLast" style="text-indent:-.25in;mso-list:l3 level1 lfo1">
<![if !supportLists]><span style="font-size:12.0pt;line-height:106%;font-family:Symbol"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span style="font-size:12.0pt;line-height:106%">A Glacios screening microscope with a Gatan K3 direct electron detector<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt">Salary and benefits are competitive based on experience.<o:p></o:p></span></p>
<div class="MsoNormal" align="center" style="text-align:center"><span style="font-size:12.0pt;font-family:"Times New Roman",serif">
<hr size="2" width="100%" align="center">
</span></div>
<p class="MsoNormal"><span style="font-size:18.0pt;font-family:"Arial",sans-serif;color:#2C6BAC">Qualifications</span><span style="font-size:12.0pt;font-family:"Times New Roman",serif"><o:p></o:p></span></p>
<p class="MsoListParagraphCxSpFirst" style="text-indent:-.25in;mso-list:l2 level1 lfo2">
<![if !supportLists]><span style="font-size:12.0pt;line-height:106%;font-family:Symbol"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span style="font-size:12.0pt;line-height:106%">A PhD in biophysics, structural biology, materials science, physics, or molecular parasitology.<o:p></o:p></span></p>
<p class="MsoListParagraphCxSpMiddle" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;mso-add-space:auto;text-indent:-.25in;line-height:normal;mso-list:l2 level1 lfo2">
<![if !supportLists]><span style="font-size:12.0pt;font-family:Symbol"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span style="font-size:12.0pt">A strong background and proven track record in one of more of the following areas: molecular parasitology of malaria parasites, single particle cryoEM, cryoET, cryoFIB-SEM milling.</span><span style="font-size:12.0pt;font-family:"Times New Roman",serif"><o:p></o:p></span></p>
<p class="MsoListParagraphCxSpMiddle" style="mso-margin-top-alt:auto;margin-bottom:0in;margin-bottom:.0001pt;mso-add-space:auto;text-indent:-.25in;line-height:normal;mso-list:l1 level1 lfo3">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span style="font-size:12.0pt">Experience with Python and/or MATLAB is a plus.</span><span style="font-size:12.0pt;font-family:"Times New Roman",serif"><o:p></o:p></span></p>
<p class="MsoListParagraphCxSpMiddle" style="mso-margin-top-alt:auto;margin-bottom:0in;margin-bottom:.0001pt;mso-add-space:auto;text-indent:-.25in;line-height:normal;mso-list:l0 level1 lfo4">
<![if !supportLists]><span style="font-size:10.0pt;font-family:Symbol"><span style="mso-list:Ignore">·<span style="font:7.0pt "Times New Roman"">
</span></span></span><![endif]><span style="font-size:12.0pt">Strong communication, interpersonal and organizational skills, and excellent attention to detail.</span><span style="font-size:12.0pt;font-family:"Times New Roman",serif"><o:p></o:p></span></p>
<p class="MsoListParagraphCxSpLast" style="mso-margin-top-alt:auto;margin-bottom:0in;margin-bottom:.0001pt;mso-add-space:auto;line-height:normal">
<span style="font-size:12.0pt;font-family:"Times New Roman",serif"><o:p> </o:p></span></p>
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<p class="MsoNormal" align="center" style="text-align:center"><span style="font-size:12.0pt;font-family:"Times New Roman",serif"><img border="0" width="721" height="176" id="Picture_x0020_1" src="cid:image003.jpg@01DAAB3F.87F65C90"></span><span style="font-size:12.0pt;font-family:"Times New Roman",serif"><o:p></o:p></span></p>
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<p class="MsoNormal"><span class="label"><span style="font-family:"Gill Sans MT",sans-serif;color:#333333;border:none windowtext 1.0pt;padding:0in;background:white">Anton et al, bioRxiv 2023,
<b>doi:</b></span></span><span style="font-family:"Gill Sans MT",sans-serif;color:#333333;background:white"> </span><a href="https://urldefense.com/v3/__https://doi.org/10.1101/2023.09.03.556115__;!!Mih3wA!F1ZPTn8nUXj34DFbA8PdYpusVM3Gduw7beN8hhIpNaI_xF-VEEvRxCbAyfb6xsx80bWNc2zPA_7CI-Lrjs4YIu0piw$"><span style="font-family:"Gill Sans MT",sans-serif;background:white">https://doi.org/10.1101/2023.09.03.556115</span></a><o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><b><span style="font-size:10.0pt;color:#44546A">Chi-Min Ho</span></b><o:p></o:p></p>
<p class="MsoNormal"><i><span style="font-size:10.0pt;color:#44546A">Assistant Professor of Microbiology & Immunology</span></i><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;color:#44546A">Columbia University, Vagelos College of Physicians & Surgeons</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;color:#44546A"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;color:#44546A">Columbia University Irving Medical Center</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;color:#44546A">701 West 168<sup>th</sup> Street</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;color:#44546A">Hammer Health Sciences Center</span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:10.0pt;color:#44546A">New York, NY 10032</span><o:p></o:p></p>
<p class="MsoNormal"><a href="https://urldefense.com/v3/__http://www.cmholab.org/__;!!Mih3wA!F1ZPTn8nUXj34DFbA8PdYpusVM3Gduw7beN8hhIpNaI_xF-VEEvRxCbAyfb6xsx80bWNc2zPA_7CI-Lrjs54aJXlaQ$" target="_blank"><span style="font-size:10.0pt;color:blue">www.cmholab.org</span></a><o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
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