[3dem] [WARNING: UNSCANNABLE EXTRACTION FAILED][REMINDER] 2-year postdoc position in AI based Protein design and Structural biology at CSIC, Madrid, Spain

[Daniel Lietha]

Daer all,

just a reminder about the position below. We will still be collecting CVs for another 2 weeks.

Best regards,
Daniel

> Begin forwarded message:
> 
> From: Daniel Lietha <daniel.lietha at cib.csic.es>
> Subject: 2-year postdoc position in AI based Protein design and Structural biology at CSIC, Madrid, Spain
> Date: 20 December 2024 at 15:24:48 CET
> To: 3dem at ncmir.ucsd.edu
> 
> Dear all,
> 
> We are seeking a motivated scientist to join our team to use artificial intelligence (AI) based methods to design novel proteins with therapeutic potential as well as to experimentally validate and characterize the designed proteins. The project is funded by Worldwide Cancer Research and aims to target regulatory sites in a well-known cancer target, known to efficiently and selectively inhibit cancer cell invasion.
> 
> The candidate will be based at the Margarita Salas Center for Biological Research (CIB-CSIC) in Madrid. She/He will work in a multidisciplinary and international team with experience in structural biology of the target (Lietha Lab, CIB-CSIC, Spain) [1], AI based protein design (Baker Lab, University of Washington, USA) [2] and relevant cancer models (Frame Lab, Cancer Research UK Edinburgh Centre) [3]. The candidate should have experience in computational structural biology, while experience with experimental biochemistry and/or structural biology techniques will be a plus.
> 
> To express your interest and send your CV or to find out more, please contact Daniel Lietha (daniel.lietha at cib.csic.es <mailto:daniel.lietha at cib.csic.es>). All enquiries and applications will be treated confidentially.
> 
> I would be very grateful if you could distribute the advertisement at your institute and among potential candidates (see also attached pdf).
> 
> Kind regards,
> Daniel
> 
> 
> References:
> 1. Acebrón I, Righetto RD, Schoenherr C, de Buhr S, Redondo P, Culley J, Rodríguez CF, Daday C, Biyani N, Llorca O, Byron A, Chami M, Gräter F, Boskovic J, Frame MC, Stahlberg H, Lietha D. Structural basis of Focal Adhesion Kinase activation on lipid membranes. EMBO J 39, e104743 (2020).
> 
> 2. Watson JL, Juergens D, Bennett NR, Trippe BL, Yim J, Eisenach HE, Ahern W, Borst AJ, Ragotte RJ, Milles LF, Wicky BIM, Hanikel N, Pellock SJ, Courbet A, Sheffler W, Wang J, Venkatesh P, Sappington I, Torres SV, Lauko A, De Bortoli V, Mathieu E, Ovchinnikov S, Barzilay R, Jaakkola TS, DiMaio F, Baek M, Baker D. De novo design of protein structure and function with RFdiffusion. Nature 620, 1089-1100 (2023).
> 
> 3. M, Dawson JC, Avalle L, Douglas AT, Mort RL, Byron A, Carragher NO, Pollard SM, Brunton VG, Frame MC. An ILK/STAT3 pathway controls glioblastoma stem cell plasticity. Dev Cell. 2024 Dec 16;59(24):3197-3212
> 
> ______________________________________________________
> Daniel Lietha, PhD
> Group Leader
> Cell Signalling and Adhesion Group
> Cellular and Molecular Biosciences
> Margarita Salas Center for Biological Research
> Spanish National Research Council (CSIC)
> Calle Ramiro de Maeztu 9, E-28040 Madrid, Spain
> Tel: + (34) 911 098 016
> Email: daniel.lietha at cib.csic.es <mailto:daniel.lietha at cib.csic.es>
> https://urldefense.com/v3/__https://cib.csic.es/research/cellular-and-molecular-biology/cell-signalling-and-adhesion__;!!Mih3wA!E0N_nXXrKGV9OF3JbyYMqIPK2Gi-wBC1xB4oIW1yq86dvL1orZzPWpUddgrFfsyVUeWzHm_An2EcUzIDUnY7ADdEsWiZsg$  <https://urldefense.com/v3/__https://cib.csic.es/research/cellular-and-molecular-biology/cell-signalling-and-adhesion__;!!Mih3wA!E0N_nXXrKGV9OF3JbyYMqIPK2Gi-wBC1xB4oIW1yq86dvL1orZzPWpUddgrFfsyVUeWzHm_An2EcUzIDUnY7ADdEsWiZsg$ >
> 
> 

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