[3dem] New game to learn/train cryo-EM/ET map resolution recognition
Leandro F. Estrozi
leandro.estrozi at ibs.fr
Tue Apr 21 09:44:44 PDT 2026
Dear colleagues,
I am pleased to share a new online training game designed for newcomers
in structural biology, with a focus on cryo-EM and cryo-ET map
interpretation:
https://urldefense.com/v3/__https://rico.ibs.fr/helixplorer/resolution/__;!!Mih3wA!EJvDy_wVZYtD-rptRWtrUxbq7A8pGA1ZjbK_kAX9nYpXHYtdekjFvrioD4obUpLP_o_2rpttEOrdDSTtQBS4juXqBm9W$
A common challenge in the field is learning to recognize whether a 3D
map is consistent with a given resolution estimate. Confusing, for
example, a 4 Å map with an 8 Å map can lead to substantial time loss
during model building and interpretation. This game was created to help
users develop an intuition for the structural features visible across
the range of resolutions typically obtained in cryo-EM/ET.
It is aimed mainly at students and beginners, but others may also find
it fun or useful as a quick training exercise.
I should note that I am fully aware that noise plays an important role
in real cryo-EM/ET data, and this first version of the game does not yet
include noise.
Feedback is very welcome. Please feel free to share it with anyone who
might be interested.
Best regards,
Leandro.
More information about the 3dem
mailing list