[3dem] postdoc position in ion channel structural biology in Vancouver, Canada

[Filip Van Petegem]

Dear colleagues,

A postdoc position is available immediately at the University of British
Columbia.


The project combines X-ray crystallography, cryo-EM, and electrophysiology.
Our lab has steady access to the in-house X-ray and cryo-EM facilities:



- Microscopes: 300kV Titan Krios with Falcon IV detector and Selectris
Energy filter.   A 200kV Glacios (Falcon III detector) is available for
prescreening grids


- X-ray equipment in the lab includes Mosquito and Dragonfly robotics, and
we have regular access to an in-house X-ray diffractor (Rigaku Micromax-007
HF with Saturn 744+ CCD detector) and various synchrotron beamlines



Minimum requirements for applicants include a PhD in Biochemistry or a
related discipline with extensive experience in either X-ray
crystallography or cryo-EM, as well as protein expression and
purification.  Direct experience with membrane proteins is an additional
plus.



The lab values diversity and inclusivity, and applicants from all
backgrounds are encouraged to apply. This is an opportunity for people with
structural biology expertise to learn electrophysiological methods.



Recent work from the lab includes an investigation of how Ryanodine
Receptors are modulated by small molecules, disease mutations, and
post-translational modification, using cryo-EM, X-ray crystallography,
planar lipid bilayer electrophysiology, and enzyme kinetics.

Woll et al (2021) *Nature Comm.* 12:807

Ma et al (2020) *Nat Chem Biol*. 16,1246-1254

Haji-Ghassemi et al (2019) *Molecular Cell* 75,1-14



For more information on recent work, see https://urldefense.proofpoint.com/v2/url?u=http-3A__crg.ubc.ca_VanPetegem_&d=DwIBaQ&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=61ykktPa_QBQUND8jLui3nRdJTFgFKkkesbIsUYZ4WuT5XkYQDle6N-BmCad-QWB&s=n5QHHrtyCOWDW5-t4Ozz9NQmDh4-WErkw_9uj4PKiXM&e= 



The lab is housed within the Life Sciences Centre at UBC (lsi.ubc.ca),
located on the Point Grey campus in Vancouver.



Interested candidates should send a CV, along with names and contact
details for 3 references to *filip.vanpetegem at gmail.com
<filip.vanpetegem at gmail.com>*.



-- 
Filip Van Petegem, PhD
Professor, Dept. of Biochemistry and Molecular Biology
The University of British Columbia
2350 Health Sciences Mall - Rm 2.356
Vancouver, V6T 1Z3

phone: +1 604 827 4267
email: filip.vanpetegem at gmail.com
https://urldefense.proofpoint.com/v2/url?u=http-3A__crg.ubc.ca_VanPetegem_&d=DwIBaQ&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=61ykktPa_QBQUND8jLui3nRdJTFgFKkkesbIsUYZ4WuT5XkYQDle6N-BmCad-QWB&s=n5QHHrtyCOWDW5-t4Ozz9NQmDh4-WErkw_9uj4PKiXM&e= 

Twitter: @FilipPetegem
-------------- next part --------------
An HTML attachment was scrubbed...
URL: <http://mail.ncmir.ucsd.edu/pipermail/3dem/attachments/20211109/ed8bca81/attachment.html>