[3dem] First call for Cryo-EM proposals at Brookhaven’s new Laboratory for BioMolecular Structure

[Liguo Wang]

Dear Researchers,

TheLaboratory for BioMolecular Structure (LBMS) 
<https://urldefense.com/v3/__https://www.bnl.gov/cryo-em/__;!!Mih3wA!WkBXyvOQ9OlEP4c9FXCITzjI2CCQedupqmGwU5KX03JmkCsFqef21b4paFwDZJ6rhA$ >at Brookhaven National Laboratoryis now 
accepting general research proposals through anopen proposal process.

This new, state-of-the-art research center offers scientists access 
toadvanced cryo-electron microscopes 
<https://urldefense.com/v3/__https://www.bnl.gov/cryo-em/instrumentation.php__;!!Mih3wA!WkBXyvOQ9OlEP4c9FXCITzjI2CCQedupqmGwU5KX03JmkCsFqef21b4paFw1SGNFzA$ >(cryo-EMs) for single 
particle analysis of proteins and macromolecular complexes, as well as 
cryo-electron tomography (cryo-ET) of cells and tissues.

LBMS operates in two 6-month cycles and all electron microscope (EM) 
time is requested each cycle through the web-basedProposal Allocation, 
Safety, and Scheduling System (PASS) <https://urldefense.com/v3/__https://pass.bnl.gov/__;!!Mih3wA!WkBXyvOQ9OlEP4c9FXCITzjI2CCQedupqmGwU5KX03JmkCsFqef21b4paFwtdRvw9w$ >system. 
There are a number ofmodes of accessfor cryo-EMs at LBMS including 
General User, Rapid Access, and Block Allocation Groupsthat all follow a 
common life cycle that involves the following steps: proposal 
submission, feasibility evaluation, peer-review, allocation of EM time, 
scheduling, carrying out the work, and reporting the results. To start, 
you need to identify the type of proposal, the technique, and the 
microscope that fits your needs.  For more details, see theLBMS User 
Guide <https://urldefense.com/v3/__https://www.bnl.gov/cryo-em/userguide/__;!!Mih3wA!WkBXyvOQ9OlEP4c9FXCITzjI2CCQedupqmGwU5KX03JmkCsFqef21b4paFydIY-PSg$ >.

*Given the uncertainties with onsite EM operations for the January – 
June (2021-1) cycle, all proposals must provide a remote access plan.*

The deadline for proposals for the 2021-1 cycle at LBMS is *Wednesday, 
September 30, 2020 at 11:59 pm New York time*. If you feel you may need 
help during the submission process, please create your proposal as early 
as possible. Please note theUser Services Office 
<https://urldefense.com/v3/__https://www.bnl.gov/ps/users/administration.php__;!!Mih3wA!WkBXyvOQ9OlEP4c9FXCITzjI2CCQedupqmGwU5KX03JmkCsFqef21b4paFwrGY2bhw$ >will be available until 
5:00 pm that day.

For instructions on how to submit proposals, see theLBMS User Guide 
<https://urldefense.com/v3/__https://www.bnl.gov/cryo-em/userguide/__;!!Mih3wA!WkBXyvOQ9OlEP4c9FXCITzjI2CCQedupqmGwU5KX03JmkCsFqef21b4paFydIY-PSg$ >. For questions regarding the 
LBMS facility, please contact Liguo Wang atlbms-em at bnl.gov 
<mailto:lbms-em at bnl.gov>.

We look forward to working with you during these exciting early years of 
LBMS operations!


LBMS

Brookhaven National Laboratory

Upton, NY 11973

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