[3dem] BSL2 vs BSL1

Sun Jul 5 23:13:03 PDT 2020

Has this been  rolled out for all the cryoem EM facility World wide? How
many facilities has been asked to fill out BSL questionnaire from TFS. Our
local service refuse to share the information with us while want to jacking
up the price.

On Mon, 6 Jul 2020, 13:52 Matthijn VOS, <matthijn.vos at pasteur.fr> wrote:

> Maybe this helps
>
> https://urldefense.com/v3/__https://consteril.com/biosafety-levels-difference/__;!!Mih3wA!RuMslxLdN3kR1D691b73ibuiBpdRTB4Pj7CJfGpPAKBAWCOWXQRf9HrT2nCmvoRzaQ$ 
>
> The difference in lab setup between BSL 1 and 2 are not that big. A lab
> manager can also decide to declare a lab BSL2 for a period of time, then
> decontaminate and resume operation as BSL1. TFS only charges extra service
> cost if microscope decontamination procedures are involved and parts can
> not be taken back. In BSL3 all parts stay in the facility until the lab
> closes. This means a company can not recover parts and reuse them. This
> will increase cost. Also decontamination procedures might damage certain
> parts that need to be replaced (other than the broken parts that needed
> fixing), which again increases cost. For BSL2 this does all not apply.
> Wearing lab coats, gloves, presence of a sink, ways to dispose of
> infectious material, a safety cabinet and modifications to the air flow I
> believe are required but are all “reversible” back to BSL1. There are no
> specifications based on disinfecting the inside of the microscope. Best is
> to contact your local TFS agent, they have a full unit for dealing with
> this, there are many BSL2 facilities worldwide that house EM.
>
> Cheers
>
> On Jul 6, 2020, at 04:21, jamon <jamonshi at gmail.com> wrote:
>
> 
>
> I heard there will be ~10% increase of service contract from BSL1 to BSL2.
> Has it been applied world wide?
>
> Regards,
>
> Jian
> On 6/7/20 9:21 am, Sherman, Michael B. wrote:
>
> Hi Ruben,
>
> Jaap is correct, BSL2 assumes standard lab practice, lab coat, gloves at
> the most, but no special safety/decon procedures. And no service cost
> increase. TFS does not want to deal with BSL3, so that is out of question.
> Our Krios is classified by TFS as level 2 instrument and my engineers come
> and go as they like (face mask is required currently… for a different
> reason). I do not see any cosequences declaring your microscope s BSL2.
>
> All the best,
>
> Misha
>
>
>
> Michael Sherman, PhD
> Dept. of Biochem. & Mol. Biology
> 1.224 Medical Research Building
> Univ. of Texas Medical Branch
> Galveston, TX 77555-1055
> Tel. 409-772-6310
> Fax: 409-772-6299
> mbsherma at UTMB.edu
>
>
>
>
>
> *From: *3dem <3dem-bounces at ncmir.ucsd.edu> <3dem-bounces at ncmir.ucsd.edu>
> on behalf of Jaap Brink <jbrink at jeol.com> <jbrink at jeol.com>
> *Date: *Sunday, July 5, 2020 at 8:10 PM
> *To: *Ruben Diaz <pindusito at gmail.com> <pindusito at gmail.com>
> *Cc: *"3dem at ncmir.ucsd.edu" <3dem at ncmir.ucsd.edu> <3dem at ncmir.ucsd.edu>
> <3dem at ncmir.ucsd.edu>
> *Subject: *Re: [3dem] BSL2 vs BSL1
>
>
>
> *WARNING:* This email originated from outside of UTMB's email system. Do
> not click links or open attachments unless you recognize the sender and
> know the content is safe.
>
>
>
> Forgot to add that before SVC enters the facility, a wipe down is
> required. Akin to what you’d do with a lab bench.
>
> Regards,
>
> Jaap
>
> ----
>
> Jacob Brink Ph.D.
>
> TEM Product Manager Life Sciences
>
> *JEOL USA, Inc.,*
>
> Peabody MA 01960, U.S.A.
>
> Cell: +1 (978) 317-9561
>
>
>
> Sent from a mobile device. Please excuse typos and this email’s brevity.
>
>
>
> On Jul 5, 2020, at 8:07 PM, Jaap Brink <jbrink at jeol.com> <jbrink at jeol.com>
> wrote:
>
> Hi Ruben,
>
>
>
> Don’t think BSL2 requires that. BSL3 for sure does and requires elaborate
> decon procedures to be in place. UTMB goes for a SVC visit back from level
> 3 to level 2. It is then safe to enter.
>
> Regards,
>
> Jaap
>
> ----
>
> Jacob Brink Ph.D.
>
> TEM Product Manager Life Sciences
>
> *JEOL USA, Inc.,*
>
> Peabody MA 01960, U.S.A.
>
> Cell: +1 (978) 317-9561
>
>
>
> Sent from a mobile device. Please excuse typos and this email’s brevity.
>
>
>
> On Jul 5, 2020, at 7:31 PM, Ruben Diaz <pindusito at gmail.com>
> <pindusito at gmail.com> wrote:
>
> Hi Jian,
>
>
>
> Yes, if we decide to put BSL2 specimens in the microscopes, we have to
> tell TFS about it, to make sure that their engineers are safe.
>
>
>
> Ruben.
>
>
>
> On Sun, Jul 5, 2020 at 5:28 PM jamon <jamonshi at gmail.com> wrote:
>
> Dear Ruben,
>
> Is it request by TFS (FEI)?
>
> Regards,
>
> Jian
>
> On 6/7/20 7:17 am, Ruben Diaz wrote:
>
> Hi all,
>
>
>
> Due to the type of samples that we are interested in imaging, it would be
> advantageous for us to declare our facility as BSL2. This designation,
> however, has some implications in terms of the paperwork and safety
> measures that have to be taken whenever service is called. Cost of course I
> am sure is another factor. Does anyone have experience as to the real
> implications that have to be considered? It is my understanding that once
> we declare the facility to be BSL2, every instrument is included in the
> designation, and it is not reversible.
>
>
>
> Any information will be greatly appreciated.
>
>
>
> Ruben.
>
>
>
> ***************************
>
> Ruben Diaz Avalos,
>
> La Jolla Institute for Immunology,
>
> 9420 Athena Cir, La Jolla, CA 92037
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