[3dem] Postdoc at Umeå University

[Linda Sandblad]

Dear all!! Wish you a lovely weekend, and just remind you about a postdoc fellowship/position, open for application until 19th August, so take the change to apply and join the Integrated Structure Biology groups https://urldefense.com/v3/__https://www.biostruct.umu.se/__;!!Mih3wA!WeWSOWIFeTK8nL7aBwVKEz6tLlRwOAAdFWAuJ6yVkpr5XJSbpZSQryuu7vXEzLiaVA$  <https://urldefense.com/v3/__https://www.biostruct.umu.se/__;!!Mih3wA!WeWSOWIFeTK8nL7aBwVKEz6tLlRwOAAdFWAuJ6yVkpr5XJSbpZSQryuu7vXEzLiaVA$ > at Umeå University, north Sweden in a interesting collaboration with Luca Jovines Lab at Karolinska institutet:
Structural dynamics of the egg coat at fertilization by cryo-ET
The aim of this project will be to shed light on fertilization by using cryo-ET to image different stages of interaction between gametes. By imaging frozen-hydrated samples, we will focus on resolving the overall architecture of the mammalian zona pellucida and related egg coats, as well as investigating how changes in the structure of these extracellular matrices contribute to the block to polyspermy.
The project will be carried out in close collaboration with Luca Jovine https://urldefense.com/v3/__http://jovinelab.org__;!!Mih3wA!WeWSOWIFeTK8nL7aBwVKEz6tLlRwOAAdFWAuJ6yVkpr5XJSbpZSQryuu7vWPRDMajQ$  <https://urldefense.com/v3/__http://jovinelab.org/__;!!Mih3wA!WeWSOWIFeTK8nL7aBwVKEz6tLlRwOAAdFWAuJ6yVkpr5XJSbpZSQryuu7vUhLAf8Qg$ > and Linda Sandblad <https://urldefense.com/v3/__https://www.umu.se/en/staff/linda-sandblad/__;!!Mih3wA!WeWSOWIFeTK8nL7aBwVKEz6tLlRwOAAdFWAuJ6yVkpr5XJSbpZSQryuu7vXsFD4HmA$ > at Umeå University associated with the Umeå Core facility for Electron Microscopy (UCEM) <https://urldefense.com/v3/__https://www.umu.se/en/research/infrastructure/umea-core-facility-for-electron-microscopy-ucem/__;!!Mih3wA!WeWSOWIFeTK8nL7aBwVKEz6tLlRwOAAdFWAuJ6yVkpr5XJSbpZSQryuu7vXyrfmb6g$ > The position will be located in the Chemical Biological Centre (KBC) building at Umeå University <https://urldefense.com/v3/__https://www.umu.se/en/chemical-biological-centre/__;!!Mih3wA!WeWSOWIFeTK8nL7aBwVKEz6tLlRwOAAdFWAuJ6yVkpr5XJSbpZSQryuu7vWQNZESaA$ >, but may also require short visits at our KI laboratory.
Available for the project are a TFS Titan Krios instrument with K2 BioQuantum detector, a Scios DualBeam SEM with Aquilos-upgraded cryo-FIB and a Leica Thunder fluorescence microscope with cryo-stage, as well as full access to all additional instruments and sample preparation equipment at both UCEM and Biochemical Imaging Centre Umeå (BICU).
Qualified applicants should have a Ph.D. degree (or be about to receive one), at least one first-author publication in a high-quality international peer-reviewed journal and documented experience in biochemistry and cryo-EM, together with strong computational skills as well as good knowledge of developmental biology. Candidates must be able to carry out independent scientific research work and to write scientific reports and manuscripts. Fluency in written and spoken English is essential. Emphasis will be placed on personal suitability, organizational skills and ability to collaborate with other members of the lab and the EM facility staff, as well as on genuine enthusiasm for the research area and methodology.
For more information about this position, please send an e-mail to luca.jovine at ki.se <mailto:luca.jovine at ki.se> and linda.sandblad at umu.se <mailto:linda.sandblad at umu.se>. To apply, please use the following link (deadline 19 August 2020):
https://urldefense.com/v3/__https://www.umu.se/en/work-with-us/fellowships-and-grants/6-1250-20__;!!Mih3wA!WeWSOWIFeTK8nL7aBwVKEz6tLlRwOAAdFWAuJ6yVkpr5XJSbpZSQryuu7vXswI-gGg$  <https://urldefense.com/v3/__https://www.umu.se/en/work-with-us/fellowships-and-grants/6-1250-20__;!!Mih3wA!WeWSOWIFeTK8nL7aBwVKEz6tLlRwOAAdFWAuJ6yVkpr5XJSbpZSQryuu7vXswI-gGg$ >

Best regards Linda
Linda Sandblad, researcher and facility director
Umeå Core Facility for Electron Microscopy, SciLifeLab Cryo-EM, NMI
Department of Chemistry, Umeå University, Sweden
Tel: +46 709324936

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