[3dem] ManifoldEM software package

Jose Maria Carazo carazo at cnb.csic.es
Thu Feb 28 08:55:10 PST 2019

Dear Ali, Abbas and Joachim

I had already positively answered you, but I did not realize -as Chuck has
done so well- that probably you were asking for a "testimonial now".

We, at Madrid, we would love to have access to your software. Not only it
addresses a foundamente issue, but it does so in a very novel way.. Your
published results are excellent, and we would be very glad not only to use
it, but to integrate it in Scipion and allowing ourselves and our users to
try it on a variate of problems. Indeed, people need to get the software to
appreciate how everything really works, otherwise it s very difficult to
imagine how to proceed further,

Wbw..JM and Carlos

On Thu, Feb 28, 2019 at 4:40 PM Sindelar, Charles <charles.sindelar at yale.edu>

> Dear Ali, Abbas, Joachim, I think I speak for all of us here at Yale
> saying we enthusiastically welcome your new software package. It is vital
> that your efforts (and cryo-EM methods development in general) receive
> strong funding support from the NIH and elsewhere, and I wholeheartedly
> back your efforts to be funded!!
> Yours, Chuck
>  ----------------------------------------------------------------------
>     Date: Wed, 27 Feb 2019 20:13:09 +0000
>     From: Ali Dashti <adashti at uwm.edu>
>     To: "3dem at ncmir.ucsd.edu" <3dem at ncmir.ucsd.edu>
>     Subject: [3dem] ManifoldEM software package
>     Message-ID:
>         <
> BN6PR16MB1858B4FE8A087DD6329E5485AD740 at BN6PR16MB1858.namprd16.prod.outlook.com
> >
>     Content-Type: text/plain; charset="iso-8859-1"
>     Dear 3DEM community members,
>     We have developed a new open source software package for the
> community. ManifoldEM applies our manifold-based approach for mapping
> energy landscapes and analysis of functionally relevant continuous
> conformational changes from single-particle data (Dashti et al. PNAS 2014<
> https://nam05.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.pnas.org%2Fcontent%2F111%2F49%2F17492.short&data=02%7C01%7Ccharles.sindelar%40yale.edu%7C53f91ad860e646616e4208d69d765d01%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C636869529041868419&sdata=YjiXP3zTxwtjDfqLyCEbEHMo3A8JByCZztPaN6iihmc%3D&reserved=0>,
> Dashti et al. BioRXiv 2019<
> https://nam05.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.biorxiv.org%2Fcontent%2F10.1101%2F291922v2.abstract&data=02%7C01%7Ccharles.sindelar%40yale.edu%7C53f91ad860e646616e4208d69d765d01%7Cdd8cbebb21394df8b4114e3e87abeb5c%7C0%7C0%7C636869529041868419&sdata=ddi0uVewugbVtUqOk4q8BwFsObj43W4NMz1e%2FQ%2BRysA%3D&reserved=0>).
> We wanted to r
>  each out to you with the news and ask if such a software were publicly
> available, would you like to receive it, and be supported in its
> installation & use?
>     We seek to secure grant funding for dissemination, workshop training,
> user support, software maintenance and further development. The statements
> of interest from the community are critical for the success of the
> application.
>     Best Regards,
>     Ali Dashti, Abbas Ourmazd and Joachim Frank
> _______________________________________________
> 3dem mailing list
> 3dem at ncmir.ucsd.edu
> https://mail.ncmir.ucsd.edu/mailman/listinfo/3dem

Prof. Jose-Maria Carazo
Biocomputing Unit, Head, CNB-CSIC
Spanish National Center for Biotechnology
Darwin 3, Universidad Autonoma de Madrid
28049 Madrid, Spain

Cell: +34639197980
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