[3dem] Cryomicroscopy Scientist, Structural Biology Platform, Francis Crick Institute, London

[Philip Walker]

*CryoEM Scientist, Structural Biology Science Technology Platform,*

*The Francis Crick Institute, London*



The Francis Crick Institute seeks to recruit a Cryo-electron Microscopy
(cryo-EM) Scientist to support single-particle and tomography projects.



The research scientist will be appointed to the Structural Biology Science
Technology Platform (SB STP), which supports the Crick in the areas of
protein science (expression and purification), biophysics, X-ray
crystallography, cryo-EM and related areas.



There are excellent opportunities for career advancement.



The Crick has a state-of-the-art facility for cryo-electron microscopy and
computation and the post will consolidate excellence in these areas. The
STP currently houses two Titan Krios 300kV microscopes each equipped with a
Volta phase plate and Falcon III detector (one has an additional Gatan
energy filter and K2 detector) and these are complemented by a Talos
Arctica 200kV microscope and a 120kV Spirit TEM screening microscope.



There are excellent facilities for computing and expertise in experimental
and computational aspects of cryo-EM being developed through the structural
biology platform with support from the Crick Scientific Computing STP.



Closing date is October 15, 2018



Details may be found here:


https://jobs.crick.ac.uk/pls/corehrrecruit//erq_jobspec_version_4.display_form?p_company=1&p_internal_external=E&p_display_in_irish=N&p_applicant_no=&p_recruitment_id=008364&p_process_type=&p_form_profile_detail=&p_display_apply_ind=Y&p_refresh_search=Y


*KEY RESPONSIBILITIES*



*These include but not limited to;*

   - Support a range of cryo-EM research activities through interaction
   with Crick scientists including cryo-EM scientists and other structural
   biologists interested in cryo-EM.
   - Contribute to management and maintenance of high-end cryo-electron
   microscopes
   - Support experimental design including sample preparation and imaging
   of biological specimens.
   - Provide expertise and support in computational image analysis.
   - Provide training in both experimental and computational aspects of
   cryo-EM.





*ABOUT US*



The Francis Crick Institute (the Crick) is a partnership between the
Medical Research Council (MRC), Cancer Research UK (CRUK), the Wellcome
Trust, University College London (UCL), Imperial College London and King’s
College London. It is a registered charity whose purpose is to conduct
biomedical research into all aspects of human health and disease.





*KEY EXPERIENCE AND COMPETENCIES*



The post holder should embody and demonstrate our core Crick values: Bold,
Imaginative, Open, Dynamic and Collegial, in addition to the following:



*Essential*

   - A higher degree in biological, physical, or engineering sciences.
   - Research experience and expertise in electron microscopy.
   - Specialist knowledge of cryo-electron microscope operation and
   high-resolution data collection.
   - Proven track record in three-dimensional electron microscopy.
   - Excellent communication skills within a research environment, building
   highly effective working relationships with scientists and support staff.
   - Plan time efficiently and be able to work both independently and in a
   team setting.

*Desirable*

   - PhD in Structural Biology or related areas.
   - Experience in data analysis single particle images and/or tomography
   data.
   - Experience with field emission gun microscopes and direct electron
   detectors.
   - Postdoctoral experience in conducting cutting-edge research in cryo-EM.
   - Authorship in peer-reviewed publications in internationally recognized
   scientific journals.
   - Specialist knowledge of cryo-EM reconstruction software.
   - Knowledge of scientific computing including Unix shell scripting,
   Matlab, Python, programming languages.
   - Flexible working practice.



*For any questions, please contact us on **jobs at crick.ac.uk*
<jobs at crick.ac.uk>*,** Phil Walker (Head, SB STP; *
*philip.walker at crick.ac.uk* <philip.walker at crick.ac.uk>*) or Peter
Rosenthal (Senior Group Leader; **peter.rosenthal at crick.ac.uk*
<peter.rosenthal at crick.ac.uk>* )*
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