<div dir="ltr"><div><b style="color:rgb(0,0,0);font-family:Calibri,Helvetica,sans-serif;font-size:16px"><span lang="EN-US" style="font-size:14pt;font-family:"Trebuchet MS""><br></span></b></div><b style="color:rgb(0,0,0);font-family:Calibri,Helvetica,sans-serif;font-size:16px"><span lang="EN-US" style="font-size:14pt;font-family:"Trebuchet MS"">CryoEM Scientist, Structural Biology Science Technology Platform,</span></b><span style="color:rgb(0,0,0);font-family:Calibri,Helvetica,sans-serif;font-size:16px"></span><div style="color:rgb(0,0,0);font-family:Calibri,Helvetica,sans-serif;font-size:16px"><p class="gmail-m_-7365006934627771679x_x_MsoNormal" style="margin:6pt 0cm"><b><span lang="EN-US" style="font-size:14pt;font-family:"Trebuchet MS"">The Francis Crick Institute, London</span></b><b><span style="font-size:14pt;font-family:"Trebuchet MS""></span></b></p><p class="gmail-m_-7365006934627771679x_x_Default" style="margin-top:0px;margin-bottom:0px"><span lang="EN-US" style="font-size:11pt"> </span><span lang="EN-US" style="font-size:11pt"><br></span></p><p class="gmail-m_-7365006934627771679x_x_Default" style="margin-top:0px;margin-bottom:0px"><span lang="EN-US" style="font-size:11pt"></span><span lang="EN-US" style="font-size:11pt">The Francis Crick Institute seeks to recruit a Cryo-electron Microscopy (cryo-EM) Scientist to support single-particle and tomography projects.</span></p><p class="gmail-m_-7365006934627771679x_x_Default" style="margin-top:0px;margin-bottom:0px;text-align:justify"><span lang="EN-US" style="font-size:11pt"> </span></p><p class="gmail-m_-7365006934627771679x_x_Default" style="margin-top:0px;margin-bottom:0px;text-align:justify"><span lang="EN-US" style="font-size:11pt">The research scientist will be appointed to the Structural Biology Science Technology Platform (SB STP), which supports the Crick in the areas of protein science (expression and purification), biophysics, X-ray crystallography, cryo-EM and related areas.</span></p><p class="gmail-m_-7365006934627771679x_x_Default" style="margin-top:0px;margin-bottom:0px;text-align:justify"><span lang="EN-US" style="font-size:11pt"> </span></p><p class="gmail-m_-7365006934627771679x_x_Default" style="margin-top:0px;margin-bottom:0px;text-align:justify"><span lang="EN-US" style="font-size:11pt">There are excellent opportunities for career advancement.</span></p><p class="gmail-m_-7365006934627771679x_x_Default" style="margin-top:0px;margin-bottom:0px;text-align:justify"><span lang="EN-US" style="font-size:11pt"> </span></p><p class="gmail-m_-7365006934627771679x_x_Default" style="margin-top:0px;margin-bottom:0px;text-align:justify"><span lang="EN-US" style="font-size:11pt">The Crick has a state-of-the-art facility for cryo-electron microscopy and computation and the post will consolidate excellence in these areas. The STP currently houses two Titan Krios 300kV microscopes each equipped with a Volta phase plate and Falcon III detector (one has an additional Gatan energy filter and K2 detector) and these are complemented by a Talos Arctica 200kV microscope and a 120kV Spirit TEM screening microscope.</span></p><p class="gmail-m_-7365006934627771679x_x_MsoNormal" style="margin-top:0px;margin-bottom:0px;text-align:justify"><span style="font-size:11pt"> </span></p><p class="gmail-m_-7365006934627771679x_x_MsoNormal" style="margin-top:0px;margin-bottom:0px;text-align:justify"><span style="font-size:11pt;font-family:"Trebuchet MS"">There are excellent facilities for computing and expertise in experimental and computational aspects of cryo-EM being developed through the structural biology platform with support from the Crick Scientific Computing STP.</span></p><p class="gmail-m_-7365006934627771679x_x_MsoNormal" style="margin-top:0px;margin-bottom:0px"><span style="font-size:11pt;font-family:"Trebuchet MS""> </span></p><p class="gmail-m_-7365006934627771679x_x_MsoNormal" style="margin-top:0px;margin-bottom:0px"><span style="font-size:11pt;font-family:"Trebuchet MS"">Closing date is October 15, 2018</span></p><p class="gmail-m_-7365006934627771679x_x_MsoNormal" style="margin-top:0px;margin-bottom:0px"><span style="font-family:"Trebuchet MS""> </span></p><p class="gmail-m_-7365006934627771679x_x_MsoNormal" style="margin-top:0px;margin-bottom:0px"><span style="font-family:"Trebuchet MS"">Details may be found here:</span></p><p class="gmail-m_-7365006934627771679x_x_MsoNormal" style="margin-top:0px;margin-bottom:0px"><span style="font-family:"Trebuchet MS""><br></span></p><p class="gmail-m_-7365006934627771679x_x_MsoNormal" style="margin-top:0px;margin-bottom:0px"><span style="font-family:"Trebuchet MS""><a href="https://jobs.crick.ac.uk/pls/corehrrecruit//erq_jobspec_version_4.display_form?p_company=1&p_internal_external=E&p_display_in_irish=N&p_applicant_no=&p_recruitment_id=008364&p_process_type=&p_form_profile_detail=&p_display_apply_ind=Y&p_refresh_search=Y" class="gmail-m_-7365006934627771679x_OWAAutoLink" id="gmail-m_-7365006934627771679LPlnk351917" target="_blank">https://jobs.crick.ac.uk/pls/corehrrecruit//erq_jobspec_version_4.display_form?p_company=1&p_internal_external=E&p_display_in_irish=N&p_applicant_no=&p_recruitment_id=008364&p_process_type=&p_form_profile_detail=&p_display_apply_ind=Y&p_refresh_search=Y</a><br></span></p></div><div style="color:rgb(0,0,0);font-family:Calibri,Helvetica,sans-serif;font-size:16px"><br></div><div style="color:rgb(0,0,0);font-family:Calibri,Helvetica,sans-serif;font-size:16px"><br><p class="gmail-m_-7365006934627771679x_x_MsoNormal" style="margin-top:0px;margin-bottom:0px;margin-left:180pt"><b><i><span style="font-family:"Trebuchet MS"">KEY RESPONSIBILITIES</span></i></b></p><p class="gmail-m_-7365006934627771679x_x_MsoNormal" style="margin-top:0px;margin-bottom:0px;margin-left:180pt"><b><i><span style="font-family:"Trebuchet MS""> </span></i></b></p><p class="gmail-m_-7365006934627771679x_x_MsoNormal" style="margin-top:0px;margin-bottom:0px;margin-left:180pt"><i><span style="font-family:"Trebuchet MS"">These include but not limited to;</span></i></p><ul><li style="margin-left:15px"><span style="font-family:"Trebuchet MS"">Support a range of cryo-EM research activities through interaction with Crick scientists including cryo-EM scientists and other structural biologists interested in cryo-EM.</span></li><li style="margin-left:15px"><span style="font-family:"Trebuchet MS"">Contribute to management and maintenance of high-end cryo-electron microscopes</span></li><li style="margin-left:15px"><span style="font-family:"Trebuchet MS"">Support experimental design including sample preparation and imaging of biological specimens.</span></li><li style="margin-left:15px"><span style="font-family:"Trebuchet MS"">Provide expertise and support in computational image analysis.</span></li><li style="margin-left:15px"><span style="font-family:"Trebuchet MS"">Provide training in both experimental and computational aspects of cryo-EM.</span></li></ul><p class="gmail-m_-7365006934627771679x_x_MsoListParagraphCxSpLast" style="margin-top:0px;margin-bottom:0.0001pt;line-height:normal"><span style="font-size:10pt;font-family:"Trebuchet MS""> </span></p><p class="gmail-m_-7365006934627771679x_x_Default" style="margin-top:0px;margin-bottom:0px;text-align:justify"><i><span lang="EN-US" style="font-size:11pt;font-family:Tahoma"> </span></i></p><p class="gmail-m_-7365006934627771679x_x_MsoNormal" style="margin-top:0px;margin-bottom:0px;margin-left:180pt"><b><i><span style="font-family:"Trebuchet MS"">ABOUT US</span></i></b></p><p class="gmail-m_-7365006934627771679x_x_MsoNormal" style="margin-top:0px;margin-bottom:0px"><b><span style="font-size:10pt;font-family:"Trebuchet MS""> </span></b></p><p class="gmail-m_-7365006934627771679x_x_Default" style="margin-top:0px;margin-bottom:0px;text-align:justify"><span lang="EN-US" style="font-size:11pt">The Francis Crick Institute (the Crick) is a partnership between the Medical Research Council (MRC), Cancer Research UK (CRUK), the Wellcome Trust, University College London (UCL), Imperial College London and King’s College London. It is a registered charity whose purpose is to conduct biomedical research into all aspects of human health and disease.</span><span lang="EN-US" style="font-size:11pt;font-family:Tahoma"></span></p><p class="gmail-m_-7365006934627771679x_x_Default" style="margin-top:0px;margin-bottom:0px;text-align:justify"><span lang="EN-US" style="font-size:11pt"> </span></p><p class="gmail-m_-7365006934627771679x_x_MsoNormal" style="margin-top:0px;margin-bottom:0px"><i><span style="font-family:"Trebuchet MS""> </span></i></p><p class="gmail-m_-7365006934627771679x_x_MsoNormal" style="margin-top:0px;margin-bottom:0px;margin-left:180pt"><b><i><span style="font-family:"Trebuchet MS"">KEY EXPERIENCE AND COMPETENCIES</span></i></b></p><p class="gmail-m_-7365006934627771679x_x_MsoNormal" style="margin-top:0px;margin-bottom:0px;margin-left:180pt"><b><i><span style="font-family:"Trebuchet MS""> </span></i></b></p><p class="gmail-m_-7365006934627771679x_x_Default" style="margin-top:0px;margin-bottom:0px"><span lang="EN-US" style="font-size:11pt;color:windowtext">The post holder should embody and demonstrate our core Crick values: Bold, Imaginative, Open, Dynamic and Collegial, in addition to the following:</span><b><span lang="EN-US" style="font-size:11pt;font-family:Tahoma;color:windowtext"></span></b></p><p class="gmail-m_-7365006934627771679x_x_MsoNormal" style="margin-top:0px;margin-bottom:0px;margin-left:180pt"><b><i><span style="font-family:"Trebuchet MS""> </span></i></b></p><p class="gmail-m_-7365006934627771679x_x_MsoNormal" style="margin:6pt 0cm"><b><span style="font-size:11pt;font-family:"Trebuchet MS"">Essential</span></b></p><ul><li style="margin-left:15px"><span style="font-family:"Trebuchet MS"">A higher degree in biological, physical, or engineering sciences.</span></li><li style="margin-left:15px"><span style="font-family:"Trebuchet MS"">Research experience and expertise in electron microscopy.</span></li><li style="margin-left:15px"><span style="font-family:"Trebuchet MS"">Specialist knowledge of cryo-electron microscope operation and high-resolution data collection.</span></li><li style="margin-left:15px"><span style="font-family:"Trebuchet MS"">Proven track record in three-dimensional electron microscopy.</span></li><li style="margin-left:15px"><span style="font-family:"Trebuchet MS"">Excellent communication skills within a research environment, building highly effective working relationships with scientists and support staff.</span></li><li style="margin-left:15px"><span style="font-family:"Trebuchet MS"">Plan time efficiently and be able to work both independently and in a team setting.</span></li></ul><p class="gmail-m_-7365006934627771679x_x_MsoNormal" style="margin:6pt 0cm"><b><span style="font-size:11pt;font-family:"Trebuchet MS"">Desirable</span></b><span style="font-size:11pt;font-family:"Trebuchet MS""></span></p><ul><li style="margin-left:15px"><span style="font-family:"Trebuchet MS"">PhD in Structural Biology or related areas.</span></li><li style="margin-left:15px"><span style="font-family:"Trebuchet MS"">Experience in data analysis single particle images and/or tomography data.</span></li><li style="margin-left:15px"><span style="font-family:"Trebuchet MS"">Experience with field emission gun microscopes and direct electron detectors.</span></li><li style="margin-left:15px"><span style="font-family:"Trebuchet MS"">Postdoctoral experience in conducting cutting-edge research in cryo-EM.</span></li><li style="margin-left:15px"><span style="font-family:"Trebuchet MS"">Authorship in peer-reviewed publications in internationally recognized scientific journals.</span></li><li style="margin-left:15px"><span style="font-family:"Trebuchet MS"">Specialist knowledge of cryo-EM reconstruction software.</span></li><li style="margin-left:15px"><span style="font-family:"Trebuchet MS"">Knowledge of scientific computing including Unix shell scripting, Matlab, Python, programming languages.</span></li><li style="margin-left:15px"><span style="font-family:"Trebuchet MS"">Flexible working practice.</span></li></ul><p class="gmail-m_-7365006934627771679x_x_MsoNormal" style="margin-top:0px;margin-bottom:0px"><span style="font-family:"Trebuchet MS""> </span></p><p class="gmail-m_-7365006934627771679x_x_MsoNormal" style="margin-top:0px;margin-bottom:0px"><b><span style="font-family:"Trebuchet MS"">For any questions, please contact us on </span></b><a href="mailto:jobs@crick.ac.uk" id="gmail-m_-7365006934627771679LPlnk954945" class="gmail-m_-7365006934627771679x_x_OWAAutoLink" target="_blank"><b><span style="font-family:"Trebuchet MS"">jobs@crick.ac.uk</span></b></a><span class="gmail-m_-7365006934627771679x_x_MsoHyperlink"><b><span style="font-family:"Trebuchet MS"">,</span></b></span><b><span style="font-family:"Trebuchet MS""> Phil Walker (Head, SB STP; </span></b><a href="mailto:philip.walker@crick.ac.uk" id="gmail-m_-7365006934627771679LPlnk690802" class="gmail-m_-7365006934627771679x_x_OWAAutoLink" target="_blank"><b><span style="font-family:"Trebuchet MS"">philip.walker@crick.ac.uk</span></b></a><b><span style="font-family:"Trebuchet MS"">) or Peter Rosenthal (Senior Group Leader; </span></b><a href="mailto:peter.rosenthal@crick.ac.uk" id="gmail-m_-7365006934627771679LPlnk571081" class="gmail-m_-7365006934627771679x_x_OWAAutoLink" target="_blank"><b><span style="font-family:"Trebuchet MS"">peter.rosenthal@crick.ac.uk</span></b></a><b><span style="font-family:"Trebuchet MS""> )</span></b></p></div></div>