[3dem] CCP-EM Position

[Tom Burnley]

http://www.topcareer.jobs/Vacancy/irc216037_6241.aspx

Salary: £36,033 – £38,426
Grade: Band E
Contract Type: Open-Ended
Hours: Full Time
Closing Date:  13/03/16
Interview Date:  01/04/16

Background

Advances in instrumentation and data processing have led to a significant
increase in the application of electron cryo-microscopy (cryo-EM), such
that it is now one of the most important experimental techniques available
in structural and cellular biology. As a result of the “resolution
revolution” good quality cryoEM data now rival crystallographic data in
terms of structural detail, while lower resolution cryoEM and electron
tomography give insights into cellular machines. To exploit fully cryo-EM
requires good scientific software for processing the primary experimental
data and for interpretating it in terms of molecular or cellular structure.
However, software provision is patchy and fragmented, and individual labs
face a steep learning curve when trying to create a suitable software
environment for their projects. To address these issues, we have
established the Collaborative Computational Project for Electron
cryo-Microscopy (CCP-EM) to support scientists, and to develop a modern
software suite. CCP-EM has been running since 2012, and has just obtained
MRC funding for a further 5 years.

CCP-EM is also providing scientific support to eBIC, the new EM facility on
the Harwell campus. eBIC follows the beamline model of the Diamond
synchrotron,  and provides visiting users with access to top-of-the-range
microscopes as well as a range of support functions.

We now seek to recruit a computational scientist to be part of the core
team of CCP-EM. Duties will include:

·         Establish good working collaborations with scientists in the UK
community
·         Contribute to the development of scientific applications in the
CCP-EM software suite
·         Research new methods and algorithms for inclusion in the suite
·         Help to integrate software from collaborating scientists into
CCP-EM
·         Work with eBIC on support for visiting scientists
·         Work with the Electron Microscopy Data Bank on validation and
deposition of structural data
·         Help with organisation of training workshops, and tutoring on
data processing and analysis
·         Helping maintain the CCP-EM website and other collaboration tools
·         Providing computational support to individual scientists, and
collaborate on biological research projects
·         Publish results in leading journals

Contacts and Communication:

The postholder will work in the Computational Biology Group of Martyn Winn
in the Scientific Computing Department of STFC. They will work closely with
other members of the group, in particular Tom Burnley for CCP-EM and others
in the CCP4 sister project.

The postholder will be supervised by Eugene Krissinel and Martyn Winn. They
will also need to report progress to the management committee of CCP-EM.

Personal Skills and Attributes:

We are looking for someone with an aptitude for computational structural
biology to undertake and develop the research and collaborations initiated
through the CCP-EM. Prior experience of biological electron cryo-microscopy
would be a distinct advantage, as would experience of related techniques
such as macromolecular crystallography or structural bioinformatics. Other
scientific backgrounds may also be acceptable if the candidate can
demonstrate an ability to learn and understand biological cryoEM. Strong
computational skills are a requirement, in order to implement scientific
ideas in robust and user-friendly software. While the focus is on
scientific methods, candidates should also have an appreciation of modern
software engineering principles.

The role is concerned with supporting a large and growing cryoEM community,
and the postholder must be able to communicate effectively with users of
cryoEM software, other software developers and with facility staff at eBIC.
They will also be required to represent CCP-EM at external meetings and
conferences. The position inevitably involves progressing a range of
activities, and so good time management is essential.

The post would suit an early career scientist who wants to be at the centre
of an exciting field at a point in time when the impact of cryoEM is
expanding rapidly.

Further information:

http://www.ccpem.ac.uk   (CCP-EM)
http://www.stfc.ac.uk/SCD (Scientific Computing Department)
http://www.stfc.ac.uk/SCD/research/app/44266.aspx   (Computational Biology
group)
http://www.diamond.ac.uk/Science/Integrated-facilities/eBIC.html (eBIC)
http://pdbe.org/emdb (Electron Microscopy Data Bank)
-------------- next part --------------
An HTML attachment was scrubbed...
URL: <http://mail.ncmir.ucsd.edu/pipermail/3dem/attachments/20160216/3fe35039/attachment.html>