[3dem] Scientist I Opening in Frederick, MD (FNLCR) - 614205

Rimorin, Lauri (NIH/NCI) [C] rimorinla at mail.nih.gov
Thu Mar 12 05:55:51 PDT 2015


Leidos Biomedical Research, Inc. (LBRI), a wholly owned subsidiary of Leidos, operates the Frederick National Laboratory for Cancer Research (FNLCR). FNLCR is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI). It is the only FFRDC dedicated to biomedical research. Through its status as an FFRDC, FNLCR provides NCI and others with a unique national resource to accelerate the development and delivery of effective preventive, diagnostic, and therapeutic products for cancer and AIDS.

The breadth of FNLCR's activities spans the research and development spectrum, including investigator-initiated, hypothesis-driven research into cancer and AIDS; advanced technology programs focused on genetics and genomics, proteins and proteomics, imaging, nanotechnology, bioinformatics, and laboratory animal sciences; clinical operations in support of NCI and National Institute of Allergy and Infectious Diseases (NIAID)-sponsored clinical trials, as well as NCI drug discovery and development efforts; and management and operations of biopharmaceutical development and manufacturing programs under current Good Manufacturing Practice conditions for NCI and NIAID. Administrative, procurement, financial, safety, and facilities support is provided to these R&D activities through state-of-the-art business processes.  LBRI has approximately 1,900 employees and manages an annual operating budget of approximately $450M.

For more information about Leidos Biomedical Research Inc., please visit our webpage at www.leidosbiomed.com<http://www.leidosbiomed.com/>.

PROGRAM DESCRIPTION

The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community. A major focus of the CRTP is the NCI RAS Initiative with the goal to discover new therapeutic interventions against RAS-driven cancers. In addition, the CRTP hosts the Nanotechnology Characterization Laboratory (NCL) which performs and standardizes preclinical efficacy and toxicity testing of nanoparticles intended for cancer therapeutics and diagnostics, and the Antibody Characterization Lab (ACL) which characterizes monoclonal antibodies or other renewable affinity binding reagents for use in cancer related research. CRTP scientists also work collaboratively with intramural NCI investigators to provide research technologies and expertise.

JOB DESCRIPTION

The Scientist I will perform: 1) negative staining and cryo-EM of proteins and protein complexes with biological sample preparation and imaging by traditional transmission electron microscopy (TEM) and scanning electron microscopy (SEM), 2) image analysis and three-dimensional reconstructions on data from negative stained specimens, cryo-electron microscopy, and electron tomography, 3) sample preparation for electron microscopy studies (negative staining, SEM, room temperature plastic embedding, cryo-electron microscopy), 4) operation of electron microscopes (SEM and TEM) and cryogenic instrumentation, 5) image analysis and three dimensional reconstructions of electron microscopy data, and 6) segmentation, interpretation and presentation of two-dimensional averages and three-dimensional volume data and fitting of high resolution data into electron density maps.

BASIC QUALIFICATIONS

  *   Possession of Doctoral degree from an accredited college or university in a field related to Computational Science, Physics, Biology or Chemistry, or eight (8) years related experience in lieu of degree
  *   Foreign degrees must be evaluated for U.S. equivalency
  *   Proficiency in biological and/or material sample preparation for electron microscopy
  *   Proficiency in the use and maintenance of transmission electron microscopes and scanning electron microscopes
  *   Strong analytical skills and ability to effectively communicate scientific results
  *   Experience with computational image analysis of electron microscopy data (e.g. Relion, Eman, Spider, Imagic, or similar)
PREFERRED QUALIFICATIONS

  *   Experience with scripting or other programming skills
  *   Experience with cryogenic liquids
  *   Experience with maintenance of advanced instrumentation
  *   Experience with single particle reconstruction from negative stain and/or cryo-EM data
To apply, please visit http://jobs.leidos.com/ShowJob/Id/443761/Scientist-I-614205-%28NCI%29/


Lauri Rimorin, PHR
Sr. Recruiter
Leidos Biomedical Research, Inc.
Frederick National Laboratory for Cancer Research
P.O. Box B, Frederick, MD 21702
Phone: 301-846-7324
Fax: 301-846-5172
lauri.rimorin at nih.gov<mailto:lauri.rimorin at nih.gov>

[http://saicf.files.wordpress.com/2013/09/204767_lbr_email_signature_official_091213.gif]

NOTE:  This communication may contain privileged or other confidential information.  If you are not the intended recipient, or believe that you have received this communication in error, please do not print, copy, retransmit, disseminate or otherwise use the information.  Please indicate to the send that you have received this email in error and delete the copy you received.


-------------- next part --------------
An HTML attachment was scrubbed...
URL: <http://mail.ncmir.ucsd.edu/pipermail/3dem/attachments/20150312/1c489b02/attachment-0001.html>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image001.gif
Type: image/gif
Size: 4672 bytes
Desc: image001.gif
URL: <http://mail.ncmir.ucsd.edu/pipermail/3dem/attachments/20150312/1c489b02/attachment-0001.gif>


More information about the 3dem mailing list