[3dem] Graphene oxide!

Henning Stahlberg henning.stahlberg at unibas.ch
Fri Apr 19 00:01:18 PDT 2013

Dear Christian,

As far as I understand, Graphene Oxide is hydrophilic, but the oxidation destroys those good properties that pristine Graphene has.
Radosav Pantelic worked on methods for making Graphene hydrophilic for use in EM, and has published a few papers on this. His most interesting paper, however, is currently still under review and should be available in the near future, hopefully. 

All the best,


Henning Stahlberg, PhD
Prof. for Structural Biology, C-CINA, Biozentrum, University Basel
Mattenstrasse 26 | D-BSSE | WRO-1058 | CH-4058 Basel | Switzerland
http://c-cina.org | Tel. +41-61-387 32 62

On Apr 19, 2013, at 12:37 AM, Christian Geiss wrote:

> Dear 3dem members,
> I would like to hydrophilize grids with graphene oxide. Does anyone has experience with it? To be more informative,
> I am interested what proportion of oxygen gives empirically the most hydrophility and is still adequate in handling. Of course,
> hydrophility appears to follow the thumb rule: the more oxygen, the better. 
> But since there are many companies that offer a broad product range for graphene oxide with lots of different quality specifications, I was wondering a bit, 
> if it is really necessary to take the product that promises the highest oxygen moiety. For instance, the oxygen ranges between 20 up to 50%
> (all are using the hammers method for oxidation of graphene), but most offer 20%. And of course, according to the producer, it is all soluble in water 
> (but I also heard that it partially can clump out in water, dependent on the level of oxygen and how large is the fraction that has been oxidized). 
> So what do you think? Can you recommend any supplier?
> Any input here would be highly appreciated,
> Christian Geiss
> Christian Geiss, M.sc.
> Universitaet Frankfurt BMLS 
> Frangakis Group 
> Max-von-Laue-Strasse 15 
> D - 60438 Frankfurt am Main 
> Phone: +49-(0)69-79842597 
> Fax:     +49-(0)69-79846467 
> geiss at biophysik.org
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