[3dem] EM Staff Scientist / Engineer position in Oxford

Kay Gruenewald kay at strubi.ox.ac.uk
Sat Jul 24 14:44:48 PDT 2010


A position for an EM Staff scientist / Engineer is available in the Oxford Particle Imaging Centre (OPIC) at the University of Oxford, UK.
Equipment in OPIC includes a FEI TF30 Polara equipped with a GIF2002 and preGIF 4K Gatan CCD, a FEI TF30 and a Jeol 2000. We are in the process of updating the detectors, including state-of-the-art direct electron detection devices and complementing the high-end microscopes by a FEI T12. Further, a Phillips CM120 in the Department of Biochemistry is also part of the Oxford multiuser facility. All microscopes are equipped with cryo-sample holders and are primarily used for cryo electron microscopic and tomographic studies of viruses and other large macromolecular complexes, both isolated and in the context of their native cellular environment. Sample preparation devices include custom made solutions from the mechanical workshop as well as a Gatan Cryoplunge 3 and a Leica high-pressure freezer.
OPIC is a unique facility in Europe: a 300kV FEG electron microscope is located in biosafety containment, enabling electron microscopic studies of human (ACDP hazard group 3) and animal (DEFRA hazard group 4) pathogens.
We are looking for an experienced electron microscopy engineer, to participate in the general service and maintenance of electron microscopy instruments and to provide training to new users. The successful applicant will have a hands on approach to routine maintenance of modern TEMs. Fault finding track record will be an advantage. Availability of further specialist training by equipment manufacturers has been negotiated. In addition, the successful applicant will participate in electron microscope hardware development projects in collaboration with mechanical and electronic workshops.
Upon interest, participation in research projects concerning structural biology data collection is possible. Our group is a Wellcome Trust funded university research group focusing on structural cell biology of virus-host interactions. We constantly improve instruments and methods, and apply them to elucidate high-resolution 3D structures of biological specimens. We are dedicated to integrate the techniques with other imaging modalities and complementary approaches.
The position is initially for 3 years and available immediately.
The Division of Structural Biology at the Wellcome Trust Centre for Human Genetics provides an active structural biology community well-linked with other centres both in Oxford and internationally. Strong local contacts exist with the Materials Science Department and the imaging groups at the Department of Biochemistry and the Dunn School of Pathology. Furthermore, we have close links to activities at the Diamond synchrotron. 

The city of Oxford has a flourishing culture, international flair and an active scientific community.

Further information is available here:
http://www.strubi.ox.ac.uk/strubi/research/gruenewald/
http://www.strubi.ox.ac.uk/
http://www.ox.ac.uk/international/oxford_british_and_international/index.html 
or by email: kay at strubi.ox.ac.uk or phone: +44-1865-287817 from Kay Grünewald.

Interested candidates please submit a CV, and a description of training and experience, and interests by email (PDF preferred) to Kay Grünewald (kay at strubi.ox.ac.uk).


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