[3dem] reserach associate position
svmcphie at utmb.edu
Tue Jan 19 14:05:08 PST 2010
A Research Associate position is available immediately in the laboratory of Svetla Stoilova-McPhie to study the structure and conformations of membrane-bound blood coagulation complexes by combining Cryo-electron microscopy and biophysical methods.
The main project will involve 2D and helical crystallization of blood coagulation factors and complexes onto functionalised lipid monolayers and lipid nanotubes, followed by Cryo-EM and structure analysis. The lipid-protein systems will be also characterised by various light scattering and spectroscopic techniques to elucidate fully the structure-function relationship in the context of membrane-binding. The Sealy Centre for Structural Biology and Molecular Biophysics at UTMB http://www.scsb.utmb.edu/, includes also a state-of-the art Cryo-EM facility. This project is furthermore in collaboration with the NCMI centre at Baylor College of Medicine, equipped with the latest technology in Cryo-EM and structure analysis: http://ncmi.bcm.tmc.edu/ncmi/. The lab has the latest model CD-spectrophotometer with fluorescence and Peltier device (Jasco J815), as well as all protein and tissue culture facilities; fluorescence and confocal microscopy.
The ideal candidate should have strong background in protein biochemistry and interest in structural biology. The successful applicant should have previous experience in protein biochemistry and analytical methods for protein analysis. Proficiency in basic biochemical techniques, HPLC, SDS-PAGE and UV-VIS spectroscopy are necessary. Excellent time management skills, strong communication and interpersonal skills are essential. Prior experience in lipid chemistry and membrane biology, as well as in fluorescence, CD and confocal microscopy or/and structural biology will be a plus, but not essential.
Candidates with Ph.D. or M.Sc. considering furthering their research career at the interface between biomedical sciences and nanotechnology are encouraged to apply.
Please send your current CV and three references to Dr. Svetla Stoilova-McPhie at svmcphie at utmb.edu<mailto:svmcphie at utmb.edu>, Department of Neuroscience and Cell Biology, University of Texas Medical Branch at Galveston: www.utmb.edu<http://www.utmb.edu/>
UTMB is also part of the Gulf Coast Consortia http://cohesion.rice.edu/centersandinst/gcc/
Svetla Stoilova-McPhie, PhD
Department of Neuroscience and Cell Biology
Scientist, Sealy Centre for Structural Biology
and Molecular Biophysics
University of Texas Medical Branch at Galveston
301 University Boulevard, Galveston, Texas 77555-0620
Cell: (+1) 281-229-2261
Fax: (1+) 409-747-2200
Email: svmcphie at utmb.edu
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