[3DEM] Post-doctoral positions at Leeds University, UK

[John Trinick]

Astbury Centre for Structural Molecular Biology, Leeds University, UK

Two post-doctoral positions are available in the 
Astbury Centre at Leeds University, UK to study 
large protein complexes by electron microscopy. 
The projects are separate but will both mainly 
use cryo-electron microscopy and single particle 
analysis. It is hoped that much of the cryo-EM 
data will be acquired using Leginon automation 
software, which is implemented on a Tecnai F20 
microscope with 4k CCD camera and in-column 
energy filter. Initial screening of different 
experimental conditions will use negative 
staining and preliminary reconstructions of both 
projects have already been obtained from stain 
data. In addition to the F20 microscope, 4 other 
TEMs are available, 2 equipped for frozen 
specimens. Data is analysed on a 150 processor 
linux cluster. 

The posts are funded for 3 (in one case 4) years 
at a starting salary of £22k-£26k (~$US39-46k) 
depending on age and experience. Previous 
experience with cryo-EM and single particle image 
processing is desirable, as is a knowledge of 
molecular biology. But applications from other 
relevant disciplines, such as materials science 
and physics, are also encouraged.

Leeds University  has one of the largest and most 
vigorous structural biology groups in Britain 
(see www.astbury.leeds.ac.uk). The University has 
25000 undergraduates and 5000 postgraduates. 
Leeds is a thriving city and the surrounding 
countryside is outstandingly beautiful.

The posts will be advertised in the press 
shortly. Informal enquiries to John Trinick



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____________________________________________________________________________
Prof. John Trinick
Astbury Centre for Structural Molecular Biology
Research Institute of Molecular and Cellular Biology
Leeds University

Office Room 6.02 Miall Building 

Postal Address
Worsley Building (Level 9)
Clarendon Way
Leeds University
Leeds LS2 9NQ, UK.

Phone/fax  44 (0)113 343 4350 (direct)

j.trinick at leeds.ac.uk

www.contractility.org



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