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--></style><title>Post-doctoral positions at Leeds University,
UK</title></head><body>
<div align="center"><font color="#000000"><b>Astbury Centre for
Structural Molecular Biology, Leeds University, UK</b></font></div>
<div><font color="#000000"><br></font></div>
<div><font color="#000000">Two post-doctoral positions are available
in the Astbury Centre at Leeds University, UK to study large protein
complexes by electron microscopy. The projects are separate but will
both mainly use cryo-electron microscopy and single particle analysis.
It is hoped that much of the cryo-EM data will be acquired using
Leginon automation software, which is implemented on a Tecnai F20
microscope with 4k CCD camera and in-column energy filter. Initial
screening of different experimental conditions will use negative
staining and preliminary reconstructions of both projects have already
been obtained from stain data. In addition to the F20 microscope, 4
other TEMs are available, 2 equipped for frozen specimens. Data is
analysed on a 150 processor linux cluster. </font></div>
<div><font color="#000000"><br></font></div>
<div><font color="#000000">The posts are funded for 3 (in one case 4)
years at a starting salary of £22k-£26k (~$US39-46k) depending on
age and experience</font>. Previous experience with cryo-EM and single
particle image processing is desirable, as is a knowledge of molecular
biology. But applications from other relevant disciplines, such as
materials science and physics, are also encouraged.</div>
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<div>Leeds University has one of the largest and most vigorous
structural biology groups in Britain (see www.astbury.leeds.ac.uk).
The University has 25000 undergraduates and 5000 postgraduates. Leeds
is a thriving city and the surrounding countryside is outstandingly
beautiful.</div>
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<div>The posts will be advertised in the press shortly. Informal
enquiries to John Trinick</div>
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>____________________________________________________________________<span
></span>________<br>
Prof. John Trinick<br>
Astbury Centre for Structural Molecular Biology<br>
Research Institute of Molecular and Cellular Biology<br>
Leeds University<br>
<br>
Office Room 6.02 Miall
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Postal Address<br>
Worsley Building (Level 9)<br>
Clarendon Way<br>
Leeds University<br>
Leeds LS2 9NQ, UK.<br>
<br>
Phone/fax 44 (0)113 343 4350 (direct)<br>
<br>
j.trinick@leeds.ac.uk<br>
<br>
www.contractility.org<br>
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