[3dem] Recruiting cryo-ET Postdoc at Ke Lab, UT Austin, Texas

[Zunlong Ke]

Dear Colleagues,

The Ke Lab<https://urldefense.com/v3/__https://www.zunlongke-lab.org/__;!!Mih3wA!C1oeiRyPF7qZLiO7ytFL3LSAXjHC9M-1k04FPKnqdY20bI5pOO49115yKIymtAy3XCOOLWAkUPuwVMzMo9467g$ > at the University of Texas at Austin, Texas seeks to recruit a highly motivated, ambitious Postdoc Fellow in virology and structural biology. Please see more details here:
https://urldefense.com/v3/__https://utaustin.wd1.myworkdayjobs.com/UTstaff/job/AUSTIN-TX/Postdoctoral-Fellow_R_00039070__;!!Mih3wA!C1oeiRyPF7qZLiO7ytFL3LSAXjHC9M-1k04FPKnqdY20bI5pOO49115yKIymtAy3XCOOLWAkUPuwVMxTztIbEw$ 

Examples of our previous and current work (including leading and contributing) on enveloped viruses using cryo-EM, cryo-ET, and subtomogram averaging:
SARS-CoV-2 Spike<https://urldefense.com/v3/__https://www.nature.com/articles/s41586-020-2665-2__;!!Mih3wA!C1oeiRyPF7qZLiO7ytFL3LSAXjHC9M-1k04FPKnqdY20bI5pOO49115yKIymtAy3XCOOLWAkUPuwVMxeoC8cvQ$ > and SARS-CoV-2 variants <https://urldefense.com/v3/__https://www.embopress.org/doi/full/10.1038/s44318-024-00303-1__;!!Mih3wA!C1oeiRyPF7qZLiO7ytFL3LSAXjHC9M-1k04FPKnqdY20bI5pOO49115yKIymtAy3XCOOLWAkUPuwVMy5KnmWiA$ > (Nature 2020, EMBO J 2024, Postdoc with John Briggs), Measles virus Matrix and Fusion glycoprotein<https://urldefense.com/v3/__https://www.nature.com/articles/s41467-018-04058-2__;!!Mih3wA!C1oeiRyPF7qZLiO7ytFL3LSAXjHC9M-1k04FPKnqdY20bI5pOO49115yKIymtAy3XCOOLWAkUPuwVMz2p-HCRQ$ > and RSV morphology and assembly<https://urldefense.com/v3/__https://www.mdpi.com/1999-4915/10/8/446__;!!Mih3wA!C1oeiRyPF7qZLiO7ytFL3LSAXjHC9M-1k04FPKnqdY20bI5pOO49115yKIymtAy3XCOOLWAkUPuwVMwpqkIXbQ$ >(Nature Comm 2018, Viruses 2018, PhD with Elizabeth Wright)
Cryo-CLEM of infected/transfected cells<https://urldefense.com/v3/__https://www.nature.com/articles/nprot.2016.168__;!!Mih3wA!C1oeiRyPF7qZLiO7ytFL3LSAXjHC9M-1k04FPKnqdY20bI5pOO49115yKIymtAy3XCOOLWAkUPuwVMy1ARqzXA$ > and Immunogold labeling for cryo-ET<https://urldefense.com/v3/__https://pubmed.ncbi.nlm.nih.gov/26069287/__;!!Mih3wA!C1oeiRyPF7qZLiO7ytFL3LSAXjHC9M-1k04FPKnqdY20bI5pOO49115yKIymtAy3XCOOLWAkUPuwVMz2S-Nf5Q$ >: with Elizabeth Wright (Nature Protocols 2017 during PhD)
Recently, our new collaborative work with Daniel Leahy at UT Austin on full-length EGFR by cryo-ET is out here at PNAS 2025<https://urldefense.com/v3/__https://www.pnas.org/doi/10.1073/pnas.2424678122__;!!Mih3wA!C1oeiRyPF7qZLiO7ytFL3LSAXjHC9M-1k04FPKnqdY20bI5pOO49115yKIymtAy3XCOOLWAkUPuwVMxHlARc6Q$ > (work at UT Austin).

About the cryo-EM and cryo-ET facility at UT Austin:
The Sauer Structural Biology Laboratory<https://urldefense.com/v3/__https://structuralbiology.cns.utexas.edu/*/__;Iw!!Mih3wA!C1oeiRyPF7qZLiO7ytFL3LSAXjHC9M-1k04FPKnqdY20bI5pOO49115yKIymtAy3XCOOLWAkUPuwVMz3LbIbbQ$ > currently hosts a Titan Krios equipped with Gatan K3 camera with energy filter, a Talos Glacios with Falcon 4 camera, a few lower-voltage TEM for negative staining, and multiple grid plunge freezing apparatus. The facility is a welcoming environment and is supported by extremely talented personnel.

The University is dedicated to expanding the cryo-EM and cryo-ET capacity. We recently purchased the following equipment and are expected to be installed this Spring and operational this Summer:

  *   An Aquilos 2 cryo-FIB/SEM, equipped with cryo-lift out and METEOR (Delmic) internal fluorescence microscope
  *   A STELLARIS 5 Cryo Confocal Light Microscope for cryo-CLEM imaging workflow
  *   A high-pressure freezer for thicker specimens
  *   A Leica GP2 for single-sided blotting of cellular materials and beyond
With the completion of the renovation, the facility will be operated at BSL2 level from sample preparation to cryo-imaging.

How to apply:
Successful postdoc applicants will hold a Ph.D. in a relevant area (e.g. virology, structural biology, biophysics) and have a strong track record of accomplishment in virology or structural biology.

Please submit your complete application documents, containing a cover letter describing your interests in my laboratory, your CV, and contact information for 3 references. Please apply here:
https://urldefense.com/v3/__https://utaustin.wd1.myworkdayjobs.com/UTstaff/job/AUSTIN-TX/Postdoctoral-Fellow_R_00039070__;!!Mih3wA!C1oeiRyPF7qZLiO7ytFL3LSAXjHC9M-1k04FPKnqdY20bI5pOO49115yKIymtAy3XCOOLWAkUPuwVMxTztIbEw$ 
Alternatively, you can email me directly. The position is available immediately.

We are also actively recruiting perspective PhD students. Informal inquiries are encouraged and can email me directly at zunlong.ke at austin.utexas.edu<mailto:zunlong.ke at austin.utexas.edu>.

Best Regards,

Zunlong Ke, PhD
Assistant Professor
CPRIT Scholar
Department of Molecular Biosciences
The University of Texas at Austin
zunlongke-lab.org<https://urldefense.com/v3/__https://www.zunlongke-lab.org/__;!!Mih3wA!C1oeiRyPF7qZLiO7ytFL3LSAXjHC9M-1k04FPKnqdY20bI5pOO49115yKIymtAy3XCOOLWAkUPuwVMzMo9467g$ >


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