[3dem] Cryo-EM Structural Discovery Facility Manager, King’s College London

[Joseph Atherton]

Cryo-EM Structural Discovery Facility Manager, King’s College London

King’s College London (KCL) is seeking a highly motivated cryo-electron microscopy (cryo-EM) expert to manage its recently established Cryo-EM Structural Discovery Facility.

At the heart of this facility is a 200 keV JEOL cryoARM200 electron microscope with an energy filter and a top-of-the-range Gatan K3 direct electron detector. This instrument is capable of producing reconstructions up to atomic resolution<https://urldefense.com/v3/__https://www.biorxiv.org/content/10.64898/2026.01.09.698548v1.full.pdf__;!!Mih3wA!B0fmOFDOxmtLdTItDAZLfQZeeOHnZA3kCYXFNt5tDt_jLHskr6m2TZYYgMOCUsbS2s_BYpvJNbCqkgl6ntl9I3SW4O1m264$ > and also acts as a “feeder” instrument for the LonCEM Titan Krios microscope at the Francis Crick Institute, where KCL has a share. The facility also includes a Leica GP2 automated vitrification system and works closely with the Centre for Ultrastructural Imaging (CUI), which houses further sample preparation methodologies such as a high-pressure freezing and CLEM systems.

About the role

This is an exciting opportunity to contribute to cutting-edge structural biology research through single-particle cryo-electron microscopy and cryo-electron tomography, while playing a pivotal role in the development and operation of the facility.

As Facility Manager, you’ll lead the operation and development of the Cryo-EM Structural Discovery Facility, running the electron microscope and managing the facility day to day, including supporting users on our sample preparation equipment. You’ll provide expert training and advice to academic and industry users, drive strategic development, optimise workflows, and implement best practices to boost efficiency and research output. You will work closely with the recently appointed academic director of the facility, Dr Joe Atherton, on developing the facility’s capabilities, academic output and financial sustainability.

We’re looking for someone with deep technical expertise in cryo-EM, including sample preparation, instrument operation, automated data acquisition, and image processing. We are particularly interested in microscopists with experience running alternatives to Thermo Fisher Scientific data collection software, such as SmartScope, SerialEM or Gatan Latitude.

This is a full-time post (35 Hours per week), and you will be offered an indefinite contract.

For more details and to apply see below!
https://urldefense.com/v3/__https://www.kcl.ac.uk/jobs/137165-cryo-em-facility-manager__;!!Mih3wA!B0fmOFDOxmtLdTItDAZLfQZeeOHnZA3kCYXFNt5tDt_jLHskr6m2TZYYgMOCUsbS2s_BYpvJNbCqkgl6ntl9I3SWZn8VG3E$ 



Dr Joe Atherton (pronouns: he/him)

Senior Lecturer in Cryo-electron Microscopy

Academic Director of KCL's Cryo-EM Structural Discovery Facility

Randall Centre for Cell and Molecular Biophysics

King's College London, UK

Email: joseph.atherton at kcl.ac.uk<mailto:joseph.atherton at kcl.ac.uk>

https://urldefense.com/v3/__https://kclpure.kcl.ac.uk/portal/joseph.atherton.html__;!!Mih3wA!B0fmOFDOxmtLdTItDAZLfQZeeOHnZA3kCYXFNt5tDt_jLHskr6m2TZYYgMOCUsbS2s_BYpvJNbCqkgl6ntl9I3SWS8CUF2U$ 


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