[3dem] Upcoming Webinar - Gene, Protein, Structure: CYP3A4 Through the Lens of Cryo-EM

[Claudio Catalano]

Hello everyone,
We would like to invite you to explore how Cryo-EM transforms challenging targets into structural insights. In this case study, we showcase the journey of CYP3A4, from gene to structure, highlighting key steps in protein preparation, sample optimization, and data collection. This work shows how we managed the oligomeric complexity of CYP3A4, a key enzyme in drug metabolism and toxicology, and uncover new structural features.
Join us to see how Cryo-EM success is built, one structure at a time.
Registration link:
https://urldefense.com/v3/__https://nimgs.zoom.us/webinar/register/4017564810214/WN_JsgAhOxgTs2fnyxwD1mTGA__;!!Mih3wA!GztVXv4rtF_Flns6rvEv0UaEcFIvQ-DVcsnewodhUUBOSmIS8oUN8FTphQfxbg36nHcjp6sOd-2WBAO9tqCehySD2Y-yf3k$ 

"Soluble Proteins in Focus: Preparing for Cryo-EM Success

Join NanoImaging Services, to get expert advice on how to set your project up for success. He will walk through each stage from protein production to structure determination, highlighting practical insights and lessons from a recent case study on CYP3A4, a 57 kDa cytochrome P450 monooxygenase that was solved to 3.1 Å."

Best,

Claudio Catalano
Senior Scientist,
NanoImaging Services & Proteos
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