[3dem] Two Fully funded PhD positions in Structural biology/ Cryo-EM/ AMR available at Leicester Institute of Structural and Chemical Biology, University of Leicester, UK

[abhinav kv]

Dear colleagues,


*Two fully funded PhD positions *(under the BBSRC MIBTP DTP program) are
available within the lab of Dr. Abhinav KV (https://urldefense.com/v3/__https://www.akv-lab.com/__;!!Mih3wA!AOJTMMZs4DkbgCIjq0Z6tUCJWs4bTXpegs5Rcp4IbR-BB3T2OzpvHAeZmhkap4hKI-aqLVU0oiYjL-KXM1daJg$ ) at
the Department of Molecular and Cell Biology (MCB) and Leicester Institute
of Structural and Chemical Biology (LISCB), University of Leicester, UK to
carry out structural studies on membrane protein complexes involved in
antimicrobial resistance (AMR) and phage therapy.  The first one involves
studying the molecular mechanism of horizontal gene transfer in bacteria
while the second one involves studying defense mechanisms bacteria have
evolved against bacteriophage infections.



*Information for both these projects can be found here: *

https://urldefense.com/v3/__https://le.ac.uk/study/research-degrees/funded-opportunities/bbsrc-mibtp__;!!Mih3wA!AOJTMMZs4DkbgCIjq0Z6tUCJWs4bTXpegs5Rcp4IbR-BB3T2OzpvHAeZmhkap4hKI-aqLVU0oiYjL-IFe_ASmA$ 



*About Us: *

The AKV-lab (https://urldefense.com/v3/__https://www.akv-lab.com/__;!!Mih3wA!AOJTMMZs4DkbgCIjq0Z6tUCJWs4bTXpegs5Rcp4IbR-BB3T2OzpvHAeZmhkap4hKI-aqLVU0oiYjL-KXM1daJg$ ) is based at MCB and LISCB within
University of Leicester (UoL), UK campus. The campus offers support for
international students and a vibrant international network. For these
interdisciplinary projects, we offer a vibrant interdisciplinary research
environment and access to world-class research facilities for biochemistry,
microbiology, biophysics, structural biology and cryo-EM. It welcomes
candidates passionate about structural biology, protein structure-function,
host-pathogen interactions, microbiology, phage-therapy and infectious
diseases. You will learn molecular cloning, advanced membrane-protein
purification techniques, *in-vitro* and *in-vivo* structural determination
of multi-megadalton nanomachines using cryo-electron microscopy (cryo-EM)
and cryo-electron tomography (cryo-ET). The projects utilize a multipronged
approach involving techniques in biophysics, cross-linking
mass-spectrometry, X-ray crystallography, integrative structural biology
and live-cell imaging to address the scientific questions. Access to
LISCB's X-ray facility and the cutting-edge microscopy infrastructure
including state-of-the-art Titan Krios 300 keV microscope enhances this
opportunity. We collaborate closely with members of the Division of
Genetics, Genomics and Cancer Sciences (GGB), University of Leicester on
these projects.



*Eligibility: *

·       A Masters (M. Sc., M. S., M. Tech) or a Bachelors (B.Sc., B. S., B.
Tech) degree in:

        Biochemistry, Molecular biology, Microbiology, Biotechnology,
Bioinformatics or related disciplines

·       Acquired previous experience working in a wet lab and excellent
command of written and spoken English.

·       Experience in recombinant protein
expression/purification/structural biology (not required but preferable).

·       A strong motivation in pursuing biological questions and
determination to actively contribute in establishing new research
directions; strong interpersonal and teamwork skills.



*Position details:*

Both positions are funded for 4 years with a start date of August 2026.
This position is open for both UK as well as international students.
Successful candidates will be provided with a full tuition-fee waiver and
an annual stipend for sustenance from BBSRC and University of Leicester,
UK. The last date of application is *27th November 2025*.



*How to apply: *Applicants will need to apply via the UoL website and more
details on the application process can be found at:
https://urldefense.com/v3/__https://le.ac.uk/study/research-degrees/funded-opportunities/bbsrc-mibtp__;!!Mih3wA!AOJTMMZs4DkbgCIjq0Z6tUCJWs4bTXpegs5Rcp4IbR-BB3T2OzpvHAeZmhkap4hKI-aqLVU0oiYjL-IFe_ASmA$ .



You can also visit the* MIBTP website (*
https://urldefense.com/v3/__https://warwick.ac.uk/fac/cross_fac/mibtp/__;!!Mih3wA!AOJTMMZs4DkbgCIjq0Z6tUCJWs4bTXpegs5Rcp4IbR-BB3T2OzpvHAeZmhkap4hKI-aqLVU0oiYjL-JElmAkmg$ ) for more details.



To know more, visit our website: https://urldefense.com/v3/__https://www.akv-lab.com/__;!!Mih3wA!AOJTMMZs4DkbgCIjq0Z6tUCJWs4bTXpegs5Rcp4IbR-BB3T2OzpvHAeZmhkap4hKI-aqLVU0oiYjL-KXM1daJg$ . We are based at
the Leicester Institute of Structural and Chemical Biology, University of
Leicester, UK:
https://urldefense.com/v3/__https://le.ac.uk/research/institutes/structural-chemical-biology__;!!Mih3wA!AOJTMMZs4DkbgCIjq0Z6tUCJWs4bTXpegs5Rcp4IbR-BB3T2OzpvHAeZmhkap4hKI-aqLVU0oiYjL-I5xUOHZw$ .



For informal enquiries, contact Dr. Abhinav KV, MCB & LISCB, University of
Leicester: akv10 at leicester.ac.uk.


Please share this announcement within your institutions or forward it to
anyone who might be interested.




Regards,

Abhinav.
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