[3dem] Nanosoft reverse action tweezers

[Walsh, Richard]

Hi Irwin,

We have a few pairs of these in our facility. New users find them easier to use; those with experience will need an adjustment period. Settings used on the Vitrobot will need to be optimized against which ever pair of tweezers you use (the positioning height of each tweezer is slightly different between the blot pads).

The pros:

  1.
easier to let go of the grid.
  2.
blunter tips are harder to ruin (better for shared use).

cons:

  1.
easier to let go of the grid.

I think it is useful to have both styles of tweezers available.


Best regards

Richard

Richard M. Walsh , Ph.D.

Managing Director
The Harvard Cryo-EM Center for Structural Biology
Harvard Medical School, 250 Longwood Avenue, SGM 105, Boston, MA 02115
Phone: (617) 432-9042
Email: Richard_Walsh at hms.harvard.edu
Web: cryoem.hms.harvard.edu
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________________________________
From: 3dem <3dem-bounces at ncmir.ucsd.edu> on behalf of Irwin Selvam via 3dem <3dem at ncmir.ucsd.edu>
Sent: Tuesday, June 3, 2025 7:26:20 AM
To: 3dem at ncmir.ucsd.edu <3dem at ncmir.ucsd.edu>
Subject: [3dem] Nanosoft reverse action tweezers


Hi all,


Has anyone used the Nanosoft reverse action tweezers for plunge freezing with a Vitrobot? How did you find them?


All the best,


Irwin
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