[3dem] Postdoctoral position available: Structural Biology of RNA-protein complexes

Tue Jul 1 14:28:41 PDT 2025

Dear Structural Biology Community,

We are seeking a talented and motivated postdoctoral scientist to join our
lab in exploring the mechanisms of RNA-protein machines important for gene
regulation using structural biology. If you know someone who might be
interested, please help us spread the word.
Thank you for your support!

Best regards,
Yunsun
Postdoctoral Positions Available
<https://urldefense.com/v3/__https://sites.google.com/ynamlab.org/web/join-us?authuser=0*h.p_hbq_Afyg84av__;Iw!!Mih3wA!FYSQpVDvGFWagdw075dAmKERx9gEPqUD70rlyohDvUvImaKC-_WtKazjFBc6X3mU6C3QF_P7d_VX3-M$ >

Biochemistry and Structural Biology of RNA-protein Complexes

A postdoctoral research position is available in the laboratory of Yunsun
Nam <https://urldefense.com/v3/__https://profiles.utsouthwestern.edu/profile/137693/yunsun-nam.html__;!!Mih3wA!FYSQpVDvGFWagdw075dAmKERx9gEPqUD70rlyohDvUvImaKC-_WtKazjFBc6X3mU6C3QF_P7FifQ5Zo$ >,
in the Department of Biochemistry
<https://urldefense.com/v3/__https://www.utsouthwestern.edu/education/medical-school/departments/biochemistry/__;!!Mih3wA!FYSQpVDvGFWagdw075dAmKERx9gEPqUD70rlyohDvUvImaKC-_WtKazjFBc6X3mU6C3QF_P712WNumo$ >
at
the University of Texas Southwestern Medical Center
<https://urldefense.com/v3/__https://www.utsouthwestern.edu/__;!!Mih3wA!FYSQpVDvGFWagdw075dAmKERx9gEPqUD70rlyohDvUvImaKC-_WtKazjFBc6X3mU6C3QF_P7dt7ZM8Y$ > in Dallas
<https://urldefense.com/v3/__https://www.utsouthwestern.edu/education/students/dallas/__;!!Mih3wA!FYSQpVDvGFWagdw075dAmKERx9gEPqUD70rlyohDvUvImaKC-_WtKazjFBc6X3mU6C3QF_P7qNoGeqI$ >, to study the
mechanisms underlying RNA-protein complexes important for gene regulation.
Our laboratory <https://urldefense.com/v3/__http://www.ynamlab.org/__;!!Mih3wA!FYSQpVDvGFWagdw075dAmKERx9gEPqUD70rlyohDvUvImaKC-_WtKazjFBc6X3mU6C3QF_P7K1s1CWc$ > works on exciting projects
dissecting the rules that govern RNA-protein recognition. We investigate
how specific RNA-protein interactions contribute to proper gene regulation.
More specifically, we investigate the core and regulatory mechanisms that
govern RNA processing (eg. microRNA and small RNA maturation via
endonucleases), modification (eg. methylation), and folding (eg. RNA
helicases) that impact the RNA function in the cell. The RNA-protein
complexes we study are relevant for normal development as well as diseases.
As we unravel how dysregulated RNA-protein complexes derail gene expression
and cause cancer, we use our mechanistic understanding to identify novel
therapeutic avenues.

To study how proteins and RNAs recognize each other, we use biochemical and
biophysical methods. Postdoctoral scholars will have opportunities to learn
the newest methods in protein and nucleic acid biochemistry and biophysics,
in addition to working in an exciting, fast-evolving field of RNA biology
and therapeutics. We use various approaches, including cryo-electron
microscopy (cryo-EM), X-ray crystallography, NMR spectroscopy, molecular
biology, nucleic acid and protein biochemistry, genomics with
next-generation sequencing, high-throughput screening for drug discovery,
and cancer cell biology. The postdoctoral fellow will have ready access to
the top-of-the-line equipment and resources necessary for the above
approaches. For cryo-EM, we have ready access to four microscopes on our
campus: two Titan Krios, one Glacios, and one Talos Arctica. Information on
our postdoctoral training program, benefits, and a virtual tour can be
found on the UTSW postdoc website
<https://urldefense.com/v3/__https://www.utsouthwestern.edu/research/postdoctoral-scholars/__;!!Mih3wA!FYSQpVDvGFWagdw075dAmKERx9gEPqUD70rlyohDvUvImaKC-_WtKazjFBc6X3mU6C3QF_P7cWGlGPU$ >.

Candidates must hold a Ph.D. or an M.D. degree. Experience in biochemistry
and structural biology leading to publication in peer-reviewed journals is
recommended. Interested individuals should email the PI (Yunsun Nam) a CV
(with publications and contact information for 3 references listed) and a
one-page cover letter that contains: ● A summary of your past research
experiences and accomplishments. ● A statement of interest in Nam Lab and
why you could be a great fit. ● Your goals for your postdoctoral training
period. ● Potential start date.

Yunsun Nam, Ph.D.

Department of Biochemistry

UT Southwestern Medical Center

Yunsun.Nam at utsouthwestern.edu

Lab Website: https://urldefense.com/v3/__http://www.ynamlab.org__;!!Mih3wA!FYSQpVDvGFWagdw075dAmKERx9gEPqUD70rlyohDvUvImaKC-_WtKazjFBc6X3mU6C3QF_P7UyJlvtc$  <https://urldefense.com/v3/__http://www.ynamlab.org/__;!!Mih3wA!FYSQpVDvGFWagdw075dAmKERx9gEPqUD70rlyohDvUvImaKC-_WtKazjFBc6X3mU6C3QF_P7K1s1CWc$ >

University Profile Page
<https://urldefense.com/v3/__https://profiles.utsouthwestern.edu/profile/137693/yunsun-nam.html__;!!Mih3wA!FYSQpVDvGFWagdw075dAmKERx9gEPqUD70rlyohDvUvImaKC-_WtKazjFBc6X3mU6C3QF_P7FifQ5Zo$ >

UT Southwestern Medical Center is committed to an educational and working
environment that provides equal opportunity to all members of the
University community. UT Southwestern prohibits unlawful discrimination,
including discrimination on the basis of race, color, religion, national
origin, sex, sexual orientation, gender identity, gender expression, age,
disability, genetic information, citizenship status, or veteran status. To
learn more, please visit here
<https://urldefense.com/v3/__https://www.utsouthwestern.edu/about-us/administrative-offices/access/equal-opportunity/__;!!Mih3wA!FYSQpVDvGFWagdw075dAmKERx9gEPqUD70rlyohDvUvImaKC-_WtKazjFBc6X3mU6C3QF_P7P2_DRoo$ >
.

Yunsun Nam
<https://urldefense.com/v3/__http://profiles.utsouthwestern.edu/profile/137693/yunsun-nam.html__;!!Mih3wA!FYSQpVDvGFWagdw075dAmKERx9gEPqUD70rlyohDvUvImaKC-_WtKazjFBc6X3mU6C3QF_P7TMKTkJQ$ >
  Associate
Professor of Biochemistry, Univ of Texas Southwestern Medical Center
https://urldefense.com/v3/__http://www.ynamlab.org__;!!Mih3wA!FYSQpVDvGFWagdw075dAmKERx9gEPqUD70rlyohDvUvImaKC-_WtKazjFBc6X3mU6C3QF_P7UyJlvtc$      5323 Harry Hines Blvd, Dallas, TX 75390-9038
Yunsun.Nam at UTSouthwestern.edu
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