[3dem] microED question (Tim Gruene)

Schenk, Andreas andreas.schenk at novartis.com
Wed Dec 10 02:25:31 PST 2025


Hi,

Another caveat is that a lot of these 273 records were solved using 2D electron crystallography (imaging or diffraction) and not using micro ED.

Best,
Andreas


> Message: 2
> Date: Wed, 10 Dec 2025 10:25:41 +0100
> From: Tim Gruene <tim.gruene at univie.ac.at>
> To: Ehsan Nikbin via 3dem <3dem at ncmir.ucsd.edu>
> Subject: Re: [3dem] microED question
> Message-ID:
> 	<20251210102541.314395db at a702-d-fibonacci.aoc.univie.ac.at>
> Content-Type: text/plain; charset="us-ascii"
> 
> Hi "",
> 
> beware of false positives with this search, and some missed entries.
> Given that most of these structures could probably placed not even with MR, but
> with a simple rigid body refinement with models from X-ray diffraction, I would not
> call many of these structures 'solved' by microED.
> 
> The ccp4bb would also be a good place for this question with qualified answer.
> 
> Best,
> Tim
> 
> 
> On Tue, 9 Dec 2025 17:18:21 +0000
> Ehsan Nikbin via 3dem <3dem at ncmir.ucsd.edu> wrote:
> 
> > Hi,
> >
> > If you filter the search in the RCSB Protein Data Bank to electron
> > crystallography, it shows 273 records out of a total of 246,045 PDB
> > entries in the archive. Hope it helps.
> >
> > Best,
> > Ehsan
> >
> >
> > ________________________________
> > From: 3dem <3dem-bounces at ncmir.ucsd.edu> on behalf of Morgan, David
> > Gene via 3dem <3dem at ncmir.ucsd.edu> Sent: Tuesday, December 9, 2025
> > 12:05 PM To: 3dem <3dem at ncmir.ucsd.edu>
> > Subject: [3dem] microED question
> >
> > Hi,
> >
> > Does anyone have an idea of the number of protein structures that have
> > been solved using microED?



More information about the 3dem mailing list