[3dem] Postdoctoral Position at the University of Illinois at Chicago | POLIKANOV Lab
Yury Polikanov
yuryp at uic.edu
Mon Apr 21 10:08:17 PDT 2025
*Postdoctoral Position Available in the Polikanov Lab
<https://urldefense.com/v3/__https://sites.google.com/view/polikanovlab__;!!Mih3wA!FbTOFW1JVF5lQTD-R-GK57Bkmoqe1WjgDOlUyYDyLrtjjpS1hyw0weqrrE1mc1JQHeSiFqyONGZWenaG$ >Department of Biological
Sciences, University of Illinois at Chicago*
*The Polikanov Laboratory <https://urldefense.com/v3/__https://sites.google.com/view/polikanovlab__;!!Mih3wA!FbTOFW1JVF5lQTD-R-GK57Bkmoqe1WjgDOlUyYDyLrtjjpS1hyw0weqrrE1mc1JQHeSiFqyONGZWenaG$ > in
the Department of Biological Sciences at the University of Illinois at
Chicago is looking for a talented, skillful, and highly motivated
researcher to fill the Postdoctoral Fellow position to study the structure
and function of the bacterial ribosome.*
For full consideration, please submit your application and cover letter
describing your scientific interests and how your previous research
accomplishments and scientific interests fit with the scope of the research
in the Polikanov research group at:
https://urldefense.com/v3/__https://uic.csod.com/ux/ats/careersite/1/home/requisition/14663?c=uic__;!!Mih3wA!FbTOFW1JVF5lQTD-R-GK57Bkmoqe1WjgDOlUyYDyLrtjjpS1hyw0weqrrE1mc1JQHeSiFqyONBS6O3RV$
*Position Summary:*
The research in the Polikanov Laboratory at UIC is focused on understanding
the basic principles of protein synthesis in bacteria, the modes of action
of ribosome-targeting antibiotics, and the mechanisms of drug resistance at
a structural level. Postdoctoral Fellow will conduct research in the
Polikanov lab and be involved in the determination of high-resolution
structures of ribosome functional complexes with various protein
translation factors, tRNAs, and antibiotics using macromolecular X-ray
crystallography and potentially cryo-EM techniques.
*Duties & Responsibilities:*
- Perform research relevant to the assigned projects;
- Act independently in planning, executing, and troubleshooting the
experiments;
- Purify bacterial ribosomes and additional components necessary for the
crystallization experiments;
- Collect X-ray diffraction data from the ribosome crystals at the APS
Synchrotron and/or collect cryo-EM data at the UChicago cryo-EM facility;
- Perform structural data analysis;
- Directly participate in writing manuscripts and grants based on the
obtained experimental data;
- Train undergraduate and graduate students in research methods, use of
equipment, record keeping, and laboratory database entry;
- Attend weekly group meetings and journal clubs.
*Minimum Qualifications:*
- PhD in biology, chemistry, biochemistry, biophysics, or a related
field; completed within the past 5 years
*Preferred Qualifications:*
- Strong background in molecular biology and biochemistry;
- Practical skills with the most standard methods currently used in
molecular biology and biochemistry (such as protein expression and
purification);
- Experience in structural biology (cryo-EM or X-ray crystallography);
- Experience in RNA biology is desired.
About the University of Illinois Chicago:
UIC is among the nation’s preeminent urban public research universities, a
Carnegie RU/VH research institution, and the largest university in Chicago.
UIC serves over 34,000 students, comprising one of the most diverse student
bodies in the nation and is designated as a Minority Serving Institution
(MSI), an Asian American and Native American Pacific Islander Serving
Institution (AANAPSI) and a Hispanic Serving Institution (HSI). Through its
16 colleges, UIC produces nationally and internationally recognized
multidisciplinary academic programs in concert with civic, corporate and
community partners worldwide, including a full complement of health
sciences colleges. By emphasizing cutting-edge and transformational
research along with a commitment to the success of all students, UIC
embodies the dynamic, vibrant and engaged urban university. Recent “Best
Colleges” rankings published by U.S. News & World Report, found UIC climbed
up in its rankings among top public schools in the nation and among all
national universities. UIC has over 300,000 alumni, and is one of the
largest employers in the city of Chicago.
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