Large Structures Meeting-Asilomar-Aprill, 2002
David DeRosier
derosier at brandeis.edu
Fri Sep 28 08:00:33 PDT 2001
The Biophysical Discussions
.......................................................................................
Frontiers in Structural Cell Biology:
Determining the structures of large subcellular machines
...................................................................
Meeting Dates: April 20-22, 2002.
Meeting Site: Asilomar, California. This is a spectacular site. You can see it at http://www.asilomarcenter.com/.
.......................................................................................
The biophysical discussions are set up so that the discussion time is greater than the times allotted for presentations, which will be available on the web prior to the meeting. The format is unusual, but highly successful.
.......................................................................................
To apply send a letter of intent to discussions at biophysics.org by November 15, 2001. Space is limited.
.......................................................................................
Organizing committee: Axel Brunger (Stanford University), David DeRosier (Brandeis University), Steve Harrison (Harvard University), and Eva Nogales (University of California at Berkeley).
The Program (Saturday, April 20, 9 am to Monday, April 22, 12 noon)
Session I. The state of structural biology of large structures.
Moderator Helen Saibil
Richard Henderson
The power of electron cryomicroscopy.
Joachim Frank
The Ribosome -- a molecular machine in motion
Jamie Cate
Biochemical basis for x-ray crystallography of the ribosome
Session II. Extending x-ray crystallography to ever larger structures
Moderator Keith Hodgson
Andy Thompson
Can we routinely collect useful data from micro-crystals?
Janos Hajdu
Future X-ray sources (tentative)
Randy Reed
The phase problem: does size matter?
Session III. New ways to obtain large complexes for structural studies
Moderator Axel Brunger
Don Wiley
Stabilizing multi-component biological complexes for structural studies by protein engineering, expression, and refolding - AND - avoiding artifacts
TBA
Expression and co-expression of components (tentative title)
Session IV. What does the future hold for electron cryomicroscopy?
Moderator Bob Glaeser
Niko Grigorieff
Single particles always fit the mold
Ken Downing
The hybrid approach to electron crystallography
Wolfgang Baumeister
Electron Tomography: Towards visualizing macromolecular assemblies inside cells
Ed Egelman
Polymorphism, can we detect it? Can we use it? Can we control it? Examples from actin and nucleoprotein complexes.
Session V. Can hybrid methods provide credible atomic models?
Moderator Eva Nogales
Niels Volkmann
Atomic model of the cell: docking in a tomographic environment
Willy Wriggers
Reconciling Shape with Structure: Morphometric Strategies for
Multi-Resolution Flexing
-------------- next part --------------
An HTML attachment was scrubbed...
URL: http://mail.ncmir.ucsd.edu/pipermail/3dem/attachments/20010928/e650d745/attachment.html
More information about the 3dem
mailing list