[3dem] did you know ACA's 75th annual meeting will be in Chicago/Lombard, IL?

Tue Mar 25 17:08:19 PDT 2025

Dear all,

The American Crystallographic Association will be holding their 75h annual meeting this year in July. Come join us at ACA's diamond celebration!

As always, the structural sciences are leading the way, and we have several sessions and workshops sponsored by the cryoEM SIG that may be of interest to you.

Do note, the deadline for oral abstracts<https://urldefense.com/v3/__https://www.acameeting2025.com/call-for-abstracts__;!!Mih3wA!AqWH3go4r_BBgjUm9jrZfM7z2eQyxphniRNPKi5zGYBbxAn6E7RMAkgAmCAv1CXCeLyw2eyq4Zw5QKc$ > is March 31st:

Innovations in sample preparation and other hardware in cryoEM
(Chairs: Ed Eng and David Taylor)

Innovations in algorithms and computational methods in cryoEM
(Chairs: Alexis Rohou and Joey Davis)

>From cells to atoms – using cryoEM approaches to address biological questions
(Chairs: Juan Du and Ben Barad)

Structure of Nucleic Acids – cryoEM
(Chairs: Melanie Ohi and Peter Hsu)

Workshop: Applications of Visualization Technology in the Structural Sciences
(Organizers:  Ed Eng and Nichole Valdez)

Find out more here: https://urldefense.com/v3/__https://www.acameeting2025.com/__;!!Mih3wA!AqWH3go4r_BBgjUm9jrZfM7z2eQyxphniRNPKi5zGYBbxAn6E7RMAkgAmCAv1CXCeLyw2eyqx5DjRh0$ 

Best,
Ed

---
Edward T. Eng, Ph.D.
Senior Scientist, Manager
New York Structural Biology Center
89 Convent Ave, NY, NY 10027
nysbc.org | (212)939-0660 x344

________________________________
From: Alexis Rohou <rohou.alexis at gene.com>
Sent: Monday, March 17, 2025 11:44 AM
To: 3dem at ncmir.ucsd.edu <3dem at ncmir.ucsd.edu>; CCPEM at jiscmail.ac.uk <CCPEM at jiscmail.ac.uk>
Cc: Ed Eng <eeng at nysbc.org>; David Taylor <dtaylor at utexas.edu>; Joey Davis <jhdavis at mit.edu>; Juan Du <juan.du at northwestern.edu>; Benjamin Barad <barad at ohsu.edu>; Melanie Ohi <mohi at umich.edu>; Peter Hsu <hsup2 at gene.com>
Subject: Re: ACA 2025 - invitation to attend & submit abstracts!

Dear colleagues,

A reminder to submit your abstracts and join us at the ACA's 75th annual meeting<https://urldefense.com/v3/__https://www.acameeting2025.com/__;!!Mih3wA!AqWH3go4r_BBgjUm9jrZfM7z2eQyxphniRNPKi5zGYBbxAn6E7RMAkgAmCAv1CXCeLyw2eyqx5DjRh0$ > in Chicago/Lombard, Illinois, July 18-23, 2025.

The CryoEM Special Interest Group is organizing several sessions<https://urldefense.com/v3/__https://www.acameeting2025.com/sessions__;!!Mih3wA!AqWH3go4r_BBgjUm9jrZfM7z2eQyxphniRNPKi5zGYBbxAn6E7RMAkgAmCAv1CXCeLyw2eyqj05FUQE$ > (see below) which could be a great home for your science. We encourage you to submit your abstracts!

The deadline for abstract submission<https://urldefense.com/v3/__https://www.acameeting2025.com/call-for-abstracts__;!!Mih3wA!AqWH3go4r_BBgjUm9jrZfM7z2eQyxphniRNPKi5zGYBbxAn6E7RMAkgAmCAv1CXCeLyw2eyq4Zw5QKc$ > is March 31st.

There are also several workshops<https://urldefense.com/v3/__https://www.acameeting2025.com/workshops__;!!Mih3wA!AqWH3go4r_BBgjUm9jrZfM7z2eQyxphniRNPKi5zGYBbxAn6E7RMAkgAmCAv1CXCeLyw2eyqGFAHS28$ > available, which may be of interest to newcomers to the field, or those looking to brush up their skills!

If you have any questions, don't hesitate to ask any of the cryoEM session co-chairs listed below.

Cheers,
Alexis

(on behalf of the cryoEM SIG and of all the session co-chairs: Ed Eng, David Taylor, Joey Davis, Juan Du, Ben Barad, Melanie Ohi and Peter Hsu)

On Mon, Feb 10, 2025 at 5:00 AM Alexis Rohou <rohoua at gene.com<mailto:rohoua at gene.com>> wrote:
Dear colleagues,

We are now accepting abstract submissions for the 2025 annual meeting of the ACA<https://urldefense.com/v3/__https://www.acameeting2025.com/__;!!Mih3wA!AqWH3go4r_BBgjUm9jrZfM7z2eQyxphniRNPKi5zGYBbxAn6E7RMAkgAmCAv1CXCeLyw2eyqx5DjRh0$ >, to be held July 18-23 in Lombard, Illinois.

Please submit your abstracts by March 31 to:
https://urldefense.com/v3/__https://auth.oxfordabstracts.com/?redirect=*stages*77680*submitter__;Ly8v!!Mih3wA!AqWH3go4r_BBgjUm9jrZfM7z2eQyxphniRNPKi5zGYBbxAn6E7RMAkgAmCAv1CXCeLyw2eyq6S4zViA$ 

The ACA is the Structural Science Society. In recent years, the ACA's annual meeting has become a wonderful home to the cryoEM community, with excellent oral and poster presentations, discussions and networking opportunities. Memorably, this led Sriram Subramaniam, one of our invited speakers in 2022, to open his remarks with "Thank you for inviting me to the annual meeting of the American CryoEM Association".

This year's meeting features numerous sessions and workshops that will be of interest to the cryoEM/cryoET community. I encourage you to take a look at the meeting's program<https://urldefense.com/v3/__https://www.acameeting2025.com/sessions__;!!Mih3wA!AqWH3go4r_BBgjUm9jrZfM7z2eQyxphniRNPKi5zGYBbxAn6E7RMAkgAmCAv1CXCeLyw2eyqj05FUQE$ >.

The cryoEM Special Interest Group (SIG) is organizing four oral sessions and one workshop, listed below. I highly encourage you, on behalf of the SIG and the co-chairs, to submit abstracts to the sessions, register for the workshop, and/or to reach out to any of us with any question you may have.

Cheers,
Alexis
(on behalf of the cryoEM SIG and of all the session co-chairs: Ed Eng, David Taylor, Joey Davis, Juan Du, Ben Barad, Melanie Ohi and Peter Hsu)

Innovations in sample preparation and other hardware in cryoEM
(Chairs: Ed Eng and David Taylor)

Advances in cryoEM and cryoET methods and technology have revolutionized our ability to see the atomic structure of proteins, and macromolecular machines in the cellular environment, respectively. Despite these breakthroughs, challenges in sample preparation and instrumentation continue to be critical areas for innovation. Join us to learn about new developments in sample preparation and other technologies that address current challenges and open doors to exciting areas of biology.

Innovations in algorithms and computational methods in cryoEM
(Chairs: Alexis Rohou and Joey Davis)

Many challenges remain in the quest to fully unlock the potential of cryoEM for structural studies of biology. How can we resolve fine details of dynamic, flexible assemblies? What is the best way to study the structures of macromolecules in their native, cellular context? How can we control our instruments more efficiently for high-throughput, automated high-resolution imaging? What are the optimal methods for obtaining and validating accurate and reliable atomic models for molecules of interest? For these and many other challenges, the development of improved computational methods and algorithms remains a key stone of the field. This session will cover some of the latest computational work in cryoEM and cryoET.

>From cells to atoms – using cryoEM approaches to address biological questions
(Chairs: Juan Du and Ben Barad)

The ability to determine 3D structures of biological systems has skyrocketed due to recent advances in cryoEM. This section will focus on the use of single particle cryo-EM and cryo-electron tomography to understand the molecular basis of biological processes.

Structure of Nucleic Acids – cryoEM
(Chairs: Melanie Ohi and Peter Hsu)

RNA, DNA, and nucleic acid-protein complexes remain challenging targets for structural biology. Nucleic acids are often structurally flexible even when complexed to their protein partners and it can be difficult to purify large enough quantities of stable nucleic acids or nucleic-protein complexes for conventional structural approaches such as NMR or X-ray crystallography. This session focuses on presenting successful examples of adopting approaches and techniques for using single particle cryo-EM to determine structures of dynamic nucleic acids and nucleic-protein complexes.

Workshop: Applications of Visualization Technology in the Structural Sciences
(Organizers:  Ed Eng and Nichole Valdez)

The Structural Science Visualization Technology Workshop at the Chicago ACA Meeting will focus on the latest advancements in visualization techniques for structural sciences, particularly in cryo-electron microscopy and X-ray crystallography. The workshop will cover cutting-edge visualization tools such as 2D and 3D molecular animations, virtual reality (VR), augmented reality (AR), and 3D printing to enhance the presentation and understanding of molecular structures. Attendees will engage in expert-led lectures, hands-on demonstrations, and discussions to explore how these technologies can be applied in scientific communication, education, and drug design.

Participants can look forward to an immersive learning experience where they will gain practical skills in using animation, VR, AR, and 3D printing to visualize complex structural data. The workshop will feature renowned experts from institutions such as the University of Utah, UC San Diego, and Schrödinger, offering insights into the latest tools like PyMOL3, syGlassVR, and Nanome.ai. Attendees will engage in interactive sessions, including hands-on demonstrations of 3D/4D visualization, molecular animations, and real-time virtual collaboration for chemical and pharmaceutical research. The event is ideal for scientists, educators, and students looking to enhance their ability to present structural data in innovative and compelling ways, making their research more accessible and impactful.

--
Alexis Rohou
Senior Principal Scientist
Director of CryoEM
Genentech, Department of Structural Biology
1 DNA Way
South San Francisco, CA 94080
Cell: 781 249 9629
Pronouns: he/him/his
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