[3dem] FAPESP Postdoctoral Position on in situ Cryo-Electron Tomography

[Andre LB Ambrosio]

Dear Colleagues,

With the Aquilos 2 cryo-FIB soon available at our Institute (link 1
<https://urldefense.com/v3/__https://www.ifsc.usp.br/alba/frontier-cryo-em-microscopes-delivered/__;!!Mih3wA!FdrC8AM35J4Nn7qEjWslJ9oB2JMB44c3HMc0fzBTWzZQSLt21-edgvMWTzftCUT5ErdSZciNylF7U4nfRRo$ >),
allow me to advertise a fellowship opportunity in my lab briefly:

*Overview*:
This project to be developed at the São Carlos Institute of Physics (IFSC),
University of São Paulo (USP) in Brazil, aims to study the in situ
structure of mitochondrial filamentous enzymes involved in the metabolic
adaptation of tumors and their effects on organelle ultrastructure and
morphology upon filamentation. This research will be an extension of
Adamoski et al., NSMB 2023 (doi: 10.1038/s41594-023-01118-0
<https://urldefense.com/v3/__https://doi.org/10.1038/s41594-023-01118-0__;!!Mih3wA!FdrC8AM35J4Nn7qEjWslJ9oB2JMB44c3HMc0fzBTWzZQSLt21-edgvMWTzftCUT5ErdSZciNylF7P-8jY58$ >), focusing on more profound
questions with cutting-edge methodologies, such as correlative
light-electron microscopy (CLEM), cryo-electron tomography in lamella
(cryo-ET) and expansion microscopy (ExM), that can also be applied to other
proteins in the lab.

*Methodological Responsibilities*:
1) Sample Preparation: Engage in cell culturing, vitrification, and
lamellae preparation in our lab at the IFSC/USP;
2) Data Collection and Processing: Perform high-resolution tomographic data
collection using top-tier microscopy facilities in Brazil and
internationally. Data processing will be done in-house.

*Requirements*:
1) PhD in Chemistry, Biochemistry, Molecular Biology, or related;
2) Experience in Cell Biology; proficiency in cryo-FIB and cryo-ET, or
single-particle cryo-EM is a big plus;
3) Strong analytical, collaboration, and English language skills.

*Details and how to apply*: link 2
<https://urldefense.com/v3/__https://www.ifsc.usp.br/alba/fapesp-postdoctoral-position-on-in-situ-cryo-electron-tomography/__;!!Mih3wA!FdrC8AM35J4Nn7qEjWslJ9oB2JMB44c3HMc0fzBTWzZQSLt21-edgvMWTzftCUT5ErdSZciNylF7DxWItrk$ >

This opportunity is open to candidates of any nationality. The selected
candidate will receive a Postdoctoral fellowship from the São Paulo
Research Foundation (FAPESP) for *R$ 9,047.40 monthly* and a research
contingency fund, equivalent to 10% of the annual value of the fellowship,
allocated for research-related expenses.

*Ref: FAPESP Fellowship Opportunity 6788 (POR/EN)*: link 3
<https://urldefense.com/v3/__https://fapesp.br/oportunidades/metabolismo_no_microambiente_e_o_papel_das_trocas_metabolicas_na_progressao_tumoral/6788/__;!!Mih3wA!FdrC8AM35J4Nn7qEjWslJ9oB2JMB44c3HMc0fzBTWzZQSLt21-edgvMWTzftCUT5ErdSZciNylF7dLJTyhM$ >

Thank you, and enjoy your week.

-- 
Andre LB Ambrosio
Associate Professor, IFSC/USP - Brazil
https://urldefense.com/v3/__http://www.ifsc.usp.br/alba__;!!Mih3wA!FdrC8AM35J4Nn7qEjWslJ9oB2JMB44c3HMc0fzBTWzZQSLt21-edgvMWTzftCUT5ErdSZciNylF7C84cHlU$ 
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