[3dem] Postdoctoral Position for CryoEM/ET of Malaria Parasites at Columbia University

Ho, Chi-Min ch3516 at cumc.columbia.edu
Thu Sep 14 10:48:08 PDT 2023


Dear Colleagues,

The Ho Lab at Columbia University is seeking a talented and enthusiastic postdoctoral research scholar to join us in using single particle cryo electron microscopy (cryoEM) and in situ cryo electron tomography (cryoET) to explore how membrane protein complexes mediate host-pathogen interactions in the Malaria parasite Plasmodium falciparum. Projects will be focused on using cryoFIB milling and cryoET to directly visualize protein complexes at the host-pathogen interface in parasite-infected human red blood cells, as well as single-particle cryoEM structure determination of native membrane protein complexes purified directly from Malaria parasites. Our lab is located in the Department of Microbiology & Immunology at Columbia University Irving Medical Center in New York City, New York. More information here: https://urldefense.com/v3/__http://www.cmholab.org/research__;!!Mih3wA!FXAeeq9o8Wnh7sWXJZbz1okY_GjRVAerNaVK08mghHf7h-Jg-_lhtzfMQJl_uqZyjJwHxMx90wEIFLa1gx-WeRyikw$ <https://urldefense.com/v3/__http://www.cmholab.org/research__;!!Mih3wA!FXAeeq9o8Wnh7sWXJZbz1okY_GjRVAerNaVK08mghHf7h-Jg-_lhtzfMQJl_uqZyjJwHxMx90wEIFLa1gx-WeRyikw$ >. To apply, please send a cover letter, CV, and contact information for three references to Dr. Chi-Min Ho at ch3516 at cumc.columbia.edu<mailto:ch3516 at cumc.columbia.edu>.


We are looking for an innovative, resourceful and resilient scientist who enjoys learning new things, meeting new people, and being part of an open, collaborative team. The successful candidate will join a vibrant, collaborative research community and enjoy access to the state-of-the-art electron microscopy facilities at Columbia, including:


  *   Multiple Titan Krios microscopes with a Gatan BioQuantum energy filter and Gatan K3 direct electron detector
  *   A dual-beam Aquilos cryo-FIB/SEM microscope, Leica cryo-correlative fluorescence light microscope
  *   A Glacios screening microscope with a Gatan K3 direct electron detector


Salary and benefits are competitive based on experience.
________________________________

Qualifications

*         A Ph.D or equivalent in biophysics, structural biology, materials science, or physics.

*         A strong background and proven track record in one of more of the following areas: single particle cryoEM, cryoET, SEM, TEM, and/or nanofabrication using a FIB-SEM or cryoFIB-SEM.

*         Experience with Python and/or MATLAB is a plus.

*         Strong communication, interpersonal and organizational skills, and excellent attention to detail.


[cid:image001.jpg at 01D9E712.1529D170]

*adapted from Anton et al, bioRxiv 2023, doi: https://urldefense.com/v3/__https://doi.org/10.1101/2023.09.03.556115__;!!Mih3wA!FXAeeq9o8Wnh7sWXJZbz1okY_GjRVAerNaVK08mghHf7h-Jg-_lhtzfMQJl_uqZyjJwHxMx90wEIFLa1gx8_474Rqg$ 

To apply, please send a cover letter, CV, and contact information for three references to Dr. Chi-Min Ho at ch3516 at cumc.columbia.edu<mailto:ch3516 at cumc.columbia.edu>. We're excited to meet you!

All the best,
~Mimi

Chi-Min Ho
Assistant Professor of Microbiology & Immunology
Columbia University, Vagelos College of Physicians & Surgeons

Columbia University Irving Medical Center
701 West 168th Street
Hammer Health Sciences Center
New York, NY 10032
https://urldefense.com/v3/__http://www.cmholab.org__;!!Mih3wA!FXAeeq9o8Wnh7sWXJZbz1okY_GjRVAerNaVK08mghHf7h-Jg-_lhtzfMQJl_uqZyjJwHxMx90wEIFLa1gx9VLCD-2Q$ <https://urldefense.com/v3/__http://www.cmholab.org/__;!!Mih3wA!FXAeeq9o8Wnh7sWXJZbz1okY_GjRVAerNaVK08mghHf7h-Jg-_lhtzfMQJl_uqZyjJwHxMx90wEIFLa1gx8zVXcYgA$ >

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