[3dem] cryo-EM facility manager position

[Olsen, Shaun K]

Dear Colleagues,

The University of Texas Health Science Center at San Antonio is seeking a co-Facility Manager for our new cryo-EM laboratory. The UTHSA cryo-EM laboratory was commissioned in 2022 and is equipped with a Thermo Fisher Scientific, 200kV Glacios TEM, with a Falcon 4 direct electron detector, and Selectris Imaging Filter, along with all standard instrumentation for single particle EM sample preparation, and has already generated data published in high-profile publications including Nature<https://urldefense.com/v3/__https://www.nature.com/articles/s41586-023-06219-w__;!!Mih3wA!HnB8JUzxtGbNLDKOH_8-5GqAgYF6q3iP4wVTmhfP6xUSgFjjdc86EKo6pPfgAjYZbLG5EkRfCFIb9ed1QzWx$ > and Nature Communications<https://urldefense.com/v3/__https://www.nature.com/articles/s41467-023-39780-z__;!!Mih3wA!HnB8JUzxtGbNLDKOH_8-5GqAgYF6q3iP4wVTmhfP6xUSgFjjdc86EKo6pPfgAjYZbLG5EkRfCFIb9Q5RTShE$ >.  We are now seeking to expand the facilities' capabilities.

The successful candidate will share responsibilities for the day-to-day running of the facility, sample preparation, data collection/processing, and user training. The candidate should be a motivated and highly interactive individual and will have the opportunity to collaborate with internal users and external researchers on a diverse set of cryo-EM-focused research projects led by world-leading investigators in cancer biology, DNA repair, immunity, ubiquitin signaling, enzymology, and drug discovery.

Preferred qualifications:
· Must have the ability to share management responsibilities for a multi-user research facility
· Must have demonstrated expertise with data collection and processing software for single particle analysis, including Relion and Cryosparc
· Previous experience with cryo-transmission electron microscope alignments and maintenance, as well as maintenance of accessory equipment is preferred
· Previous experience training students and staff in the operation of cryo-transmission electron microscopes and downstream data processing/analysis is preferred
· Strong communication and organization skills to enable timely communication with faculty, students, staff, vendors, and service engineers, accurate and clear record keeping, and active participation in the planning and writing of manuscripts and center-related grant proposals as needed
· Scholarship to keep abreast of scientific literature concerning relevant new instrumentation, data processing, specimen preparation and imaging techniques.

This position provides attractive salary (commensurate with experience and qualifications) and generous benefits.

Interested candidates should e-mail a cover letter, CV, and the names of three references to olsens at uthscsa.edu<mailto:olsens at uthscsa.edu>.

Sincerely,

Shaun K. Olsen, PhD
Associate Professor
Department of Biochemistry & Structural Biology
UT Health San Antonio
San Antonio, TX 78229
olsens at uthscsa.edu<mailto:olsens at uthscsa.edu>

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