[3dem] Postdoc positions at Helmholtz Munich: Cryo-EM and integrative structural biology to study small molecule control of alternative splicing

[Michael Sattler]

Postdoc positions at Helmholtz Munich: Cryo-EM and integrative structural biology to study small molecule control of alternative splicing

The ERC Synergy/UKRI project UNLEASH studies mechanisms and small molecule modulation of alternative pre-mRNA splicing in human cells.
Postdoc positions are available in the Sattler group at Helmholtz Munich to study (early) spliceosome complexes and small molecule interactions combining cryo-EM and integrative structural biology.

Access to outstanding cryo-EM, computational infrastructure,
(https://urldefense.com/v3/__https://www.helmholtz-munich.de/en/research/cryo-electron-microscopy-platform-at-helmholtz-munich__;!!Mih3wA!CVosBt37VceZ06aFS__NrhwKl2SYMnAcWk22yFmBGYU8wgkAyhCCRbWISXKT0JF0geUtxJ_qwhwhnmLgFmIKhcddUCIMdjMEBPNlunJ3$ ),
NMR (https://urldefense.com/v3/__http://www.bnmrz.org__;!!Mih3wA!CVosBt37VceZ06aFS__NrhwKl2SYMnAcWk22yFmBGYU8wgkAyhCCRbWISXKT0JF0geUtxJ_qwhwhnmLgFmIKhcddUCIMdjMEBHKN1p09$ <https://urldefense.com/v3/__http://www.bnmrz.org__;!!Mih3wA!CVosBt37VceZ06aFS__NrhwKl2SYMnAcWk22yFmBGYU8wgkAyhCCRbWISXKT0JF0geUtxJ_qwhwhnmLgFmIKhcddUCIMdjMEBHKN1p09$ >), and state-of-the-art wet-lab facilities is available in a stimulating and thriving scientific environment and collaboration with our UNLEASH partners at CRG Barcelona (Juan Valcarcel), and University of Dundee (Angus Lamond and David Gray).

Candidates should have excellent protein and RNA biochemistry expertise, including experience with eukaryotic cell culture, in vitro transcription and reconstitution or cellular purification of protein-RNA complexes for biochemical and structural studies. Demonstrated expertise with cryo-EM single-particle analysis is important.

Further information and application:
https://urldefense.com/v3/__https://jobs.helmholtz-muenchen.de/jobposting/b1f50264d8f7ea3336551d638edc41c38f7eab8d0__;!!Mih3wA!CVosBt37VceZ06aFS__NrhwKl2SYMnAcWk22yFmBGYU8wgkAyhCCRbWISXKT0JF0geUtxJ_qwhwhnmLgFmIKhcddUCIMdjMEBD1cv-Dj$ 

Michael Sattler

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Prof. Dr. Michael Sattler

Assistant: Karen Biniossek
E-mail: karen.biniossek at helmholtz-munich.de<mailto:karen.biniossek at helmholtz-munich.de>
Tel: +49 89 289-52601       Fax: +49 89 289-52669

Helmholtz Munich
Molecular Targets and Therapeutics Center
Institute of Structural Biology
Ingolstädter Landstr. 1, 85764 Neuherberg
Tel.: +49 89 3187-3800            https://urldefense.com/v3/__http://www.helmholtz-munich.de/stb__;!!Mih3wA!CVosBt37VceZ06aFS__NrhwKl2SYMnAcWk22yFmBGYU8wgkAyhCCRbWISXKT0JF0geUtxJ_qwhwhnmLgFmIKhcddUCIMdjMEBEPxlJ-x$ 

Technical University of Munich
TUM School of Natural Sciences, Department of Bioscience
Bayerisches NMR Zentrum     https://urldefense.com/v3/__http://www.bnmrz.org__;!!Mih3wA!CVosBt37VceZ06aFS__NrhwKl2SYMnAcWk22yFmBGYU8wgkAyhCCRbWISXKT0JF0geUtxJ_qwhwhnmLgFmIKhcddUCIMdjMEBHKN1p09$ 
Mail:       Lichtenbergstrasse 4, 85748 Garching
Building: Ernst-Otto-Fischer-Straße 2, 85748 Garching
Tel.: +49 89 289-52600            https://urldefense.com/v3/__https://www.sattlerlab.de/__;!!Mih3wA!CVosBt37VceZ06aFS__NrhwKl2SYMnAcWk22yFmBGYU8wgkAyhCCRbWISXKT0JF0geUtxJ_qwhwhnmLgFmIKhcddUCIMdjMEBGKTGq8_$ 
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Helmholtz Zentrum München – Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Ingolstädter Landstraße 1, D-85764 Neuherberg, https://urldefense.com/v3/__https://www.helmholtz-munich.de__;!!Mih3wA!CVosBt37VceZ06aFS__NrhwKl2SYMnAcWk22yFmBGYU8wgkAyhCCRbWISXKT0JF0geUtxJ_qwhwhnmLgFmIKhcddUCIMdjMEBIHcUhQn$ 
Geschäftsführung: Prof. Dr. med. Dr. h.c. Matthias H. Tschöp, Prof. Dr. Dr. h.c. mult. Martin Hrabě de Angelis (komm.) | Aufsichtsratsvorsitzende: MinDir’in Prof. Dr. Veronika von Messling
Registergericht: Amtsgericht München HRB 6466 | USt-IdNr. DE 129521671
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