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<b>Postdoc positions at Helmholtz Munich: Cryo-EM and integrative structural biology to study small molecule control of alternative splicing
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The ERC Synergy/UKRI project UNLEASH studies mechanisms and small molecule modulation of alternative pre-mRNA splicing in human cells.
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Postdoc positions are available in the Sattler group at Helmholtz Munich to study (early) spliceosome complexes and small molecule interactions combining cryo-EM and integrative structural biology.
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Access to outstanding cryo-EM, computational infrastructure, <br>
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mso-tstyle-colband-size:0;
mso-style-noshow:yes;
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mso-ascii-theme-font:minor-latin;
mso-hansi-font-family:Cambria;
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<![endif]-->),
and state-of-the-art wet-lab facilities is available in a stimulating and thriving scientific environment and collaboration with our UNLEASH partners at CRG Barcelona (Juan Valcarcel), and University of Dundee (Angus Lamond and David Gray).<br>
<br>
Candidates should have excellent protein and RNA biochemistry expertise, including experience with eukaryotic cell culture, in vitro transcription and reconstitution or cellular purification of protein-RNA complexes for biochemical and structural studies. Demonstrated
expertise with cryo-EM single-particle analysis is important. <br>
<br>
Further information and application: <br>
<a class="moz-txt-link-freetext" href="https://urldefense.com/v3/__https://jobs.helmholtz-muenchen.de/jobposting/b1f50264d8f7ea3336551d638edc41c38f7eab8d0__;!!Mih3wA!CVosBt37VceZ06aFS__NrhwKl2SYMnAcWk22yFmBGYU8wgkAyhCCRbWISXKT0JF0geUtxJ_qwhwhnmLgFmIKhcddUCIMdjMEBD1cv-Dj$">https://jobs.helmholtz-muenchen.de/jobposting/b1f50264d8f7ea3336551d638edc41c38f7eab8d0</a><br>
<br>
Michael Sattler<br>
<br>
<div class="moz-signature">-- <br>
<title>signature</title>
<font size="-2"><font face="Helvetica, Arial, sans-serif">-----------------------------------<br>
Prof. Dr. Michael Sattler<br>
<br>
Assistant: Karen Biniossek<br>
E-mail: <a class="moz-txt-link-abbreviated" href="mailto:karen.biniossek@helmholtz-munich.de">
karen.biniossek@helmholtz-munich.de</a><br>
Tel: +49 89 289-52601 Fax: +49 89 289-52669 <br>
<br>
Helmholtz Munich<br>
Molecular Targets and Therapeutics Center<br>
Institute of Structural Biology<br>
Ingolstädter Landstr. 1, 85764 Neuherberg<br>
Tel.: +49 89 3187-3800 <a class="moz-txt-link-freetext" href="https://urldefense.com/v3/__http://www.helmholtz-munich.de/stb__;!!Mih3wA!CVosBt37VceZ06aFS__NrhwKl2SYMnAcWk22yFmBGYU8wgkAyhCCRbWISXKT0JF0geUtxJ_qwhwhnmLgFmIKhcddUCIMdjMEBEPxlJ-x$">
http://www.helmholtz-munich.de/stb</a> <br>
<br>
Technical University of Munich<br>
TUM School of Natural Sciences, Department of Bioscience <br>
Bayerisches NMR Zentrum <a class="moz-txt-link-freetext" href="https://urldefense.com/v3/__http://www.bnmrz.org__;!!Mih3wA!CVosBt37VceZ06aFS__NrhwKl2SYMnAcWk22yFmBGYU8wgkAyhCCRbWISXKT0JF0geUtxJ_qwhwhnmLgFmIKhcddUCIMdjMEBHKN1p09$">
http://www.bnmrz.org</a><br>
Mail: Lichtenbergstrasse 4, 85748 Garching <br>
Building: Ernst-Otto-Fischer-Straße 2, 85748 Garching<br>
Tel.: +49 89 289-52600 <a class="moz-txt-link-freetext" href="https://urldefense.com/v3/__https://www.sattlerlab.de/__;!!Mih3wA!CVosBt37VceZ06aFS__NrhwKl2SYMnAcWk22yFmBGYU8wgkAyhCCRbWISXKT0JF0geUtxJ_qwhwhnmLgFmIKhcddUCIMdjMEBGKTGq8_$">
https://www.sattlerlab.de/</a><br>
-----------------------------------</font><br>
<br>
</font></div>
<p><font size="-1"><b>Helmholtz Zentrum München</b> – <b>Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)</b><br>
Ingolstädter Landstraße 1, D-85764 Neuherberg, <a href="https://urldefense.com/v3/__https://www.helmholtz-munich.de__;!!Mih3wA!CVosBt37VceZ06aFS__NrhwKl2SYMnAcWk22yFmBGYU8wgkAyhCCRbWISXKT0JF0geUtxJ_qwhwhnmLgFmIKhcddUCIMdjMEBIHcUhQn$">
https://www.helmholtz-munich.de</a><br>
Geschäftsführung: Prof. Dr. med. Dr. h.c. Matthias H. Tschöp, Prof. Dr. Dr. h.c. mult. Martin Hrabě de Angelis (komm.) | Aufsichtsratsvorsitzende: MinDir’in Prof. Dr. Veronika von Messling<br>
Registergericht: Amtsgericht München HRB 6466 | USt-IdNr. DE 129521671 </font></p>
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