[3dem] Postdoctoral position in structural bioinformatics at RCSB @ UCSF

Ben Webb ben at salilab.org
Fri Feb 11 16:56:09 PST 2022


Dear colleagues,

The research group of Andrej Sali at UCSF (https://urldefense.proofpoint.com/v2/url?u=https-3A__salilab.org&d=DwICaQ&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=WY8fUqhhCXebwxBBdF47NbxY3Q1A3-zuyvDseMxpsHhWrAZyIvvRGBBVW5bDgwb_&s=HxWy_SVATfs5SjaDsjfM67XmdRW60R9FDl8fKdDIKS4&e= ) is 
seeking a highly motivated postdoctoral researcher in bioinformatics, 
with domain experience in structural biology. The candidate should be 
interested in structural biological data and enjoy engaging with other 
programmers and scientists in a collaborative team environment. The 
position is part of the RCSB Protein Data Bank (https://urldefense.proofpoint.com/v2/url?u=https-3A__rcsb.org&d=DwICaQ&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=WY8fUqhhCXebwxBBdF47NbxY3Q1A3-zuyvDseMxpsHhWrAZyIvvRGBBVW5bDgwb_&s=04SUBZWpOgPXWyxudMyhbat0ZcgQjzC9Q7lVobuRxDY&e= ) effort 
at University of California, San Francisco, focused on the development 
of resources for the integrative methods initiative of worldwide Protein 
Data Bank. The effort has already produced a number of scientific 
publications, and is expected to provide ample opportunities for 
additional first-author publications in the future, including in 
Bayesian validation of structural models in general, one of the 
frontiers in structural biology.

Responsibilities:

   - Design, development, and deployment of the nascent archive for
     integrative structures at the Protein Data Bank, PDB-Dev
     (https://pdb-dev.wwpdb.org)
   - Integration of complex bioinformatics data, implementation of
     specialized algorithms for search/data analysis and use of AI tools
   - Design and implementation of cloud-ready deployments usin
     containerization and modern cloud technologies
   - Analysis, refactoring and adaptation of legacy code to conform to
     new architecture designs
   - Debugging, testing, troubleshooting

Qualifications:

   - PhD in Computer Science, Biochemistry, Bioinformatics, or a related
     discipline, or a comparable combination of education and experience
     developing modern scientific data applications
   - Excellent interpersonal, verbal, and written communication skills
   - Experience with Python, document databases, search and data access
     tools

Scientific background in any of the following areas would be considered 
a major plus: Molecular Biology, Bioinformatics, Cheminformatics, 
Biochemistry, Chemistry, Genomics. Experience working with large and 
complex scientific datasets would also be considered a plus.

Outstanding Benefits Package. UCSF is a friendly and collaborative 
working environment with excellent professional development 
opportunities. There are personal rewards including a comprehensive 
health plan.

About the Sali research group at UCSF: https://urldefense.proofpoint.com/v2/url?u=https-3A__salilab.org&d=DwICaQ&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=WY8fUqhhCXebwxBBdF47NbxY3Q1A3-zuyvDseMxpsHhWrAZyIvvRGBBVW5bDgwb_&s=HxWy_SVATfs5SjaDsjfM67XmdRW60R9FDl8fKdDIKS4&e= .

About RCSB PDB: The work at RCSB PDB (https://urldefense.proofpoint.com/v2/url?u=https-3A__rcsb.org&d=DwICaQ&c=-35OiAkTchMrZOngvJPOeA&r=L7-zyQ-04fFCMRqzLIOnx7H0exGZHwIQe_wMPuY600I&m=WY8fUqhhCXebwxBBdF47NbxY3Q1A3-zuyvDseMxpsHhWrAZyIvvRGBBVW5bDgwb_&s=04SUBZWpOgPXWyxudMyhbat0ZcgQjzC9Q7lVobuRxDY&e= ) focuses on data 
analysis, integration, and transformation, and the presentation and 
visualization of data using complex interactive graphical user 
interfaces. An important aspect is to provide users with the ability to 
search and explore the PDB data archive. Solutions are implemented using 
a wide range of components developed and maintained in-house, in 
addition to third-party tools, libraries, frameworks and technologies. 
The candidate should be comfortable working in a dynamic environment, 
and able to demonstrate an ability to think creatively, generate new 
ideas, and implement solutions. The candidate should also show an 
eagerness to learn new skills and technologies.

Apply: Please send an email with a cover letter and cv to Andrej Sali at 
sali at salilab.org.


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