[3dem] Postdoctoral position in cryo-EM structural biology at Harvard Medical School

[Weitz, Charles J.]

Postdoctoral position in cryo-EM structural biology at Harvard Medical School

We are seeking an outstanding, highly-motivated postdoctoral fellow to join our team in the cryo-EM structural analysis of the endogenous protein complexes comprising the mammalian circadian clock, a molecular oscillator present in all or nearly all cells that drives daily rhythms of gene expression, physiology, and behavior.
Applicants should have a Ph.D. degree and expertise in biochemistry and structural biology, including substantial experience in cryo-EM structure determination.  Our initial studies (e.g., Aryal et al., Mol. Cell, 2017) provided the first basic structural characterization of native circadian clock machinery from a eukaryote.  We have made progress in single-particle cryo-EM analysis of native circadian clock complexes purified from mouse tissues, and we aim to obtain high-resolution structures.  A successful outcome would have a major impact on our understanding of the mechanism of biological timekeeping.
Interested candidates should contact Chuck Weitz at cweitz at hms.harvard.edu<mailto:cweitz at hms.harvard.edu>.   Please include a cover letter, Curriculum Vitae, and a brief statement of research expertise and interests.

______________________________
Charles J. Weitz, M.D., Ph.D.
Robert Henry Pfeiffer Professor
Department of Neurobiology
Harvard Medical School
220 Longwood Ave.
Boston, MA 02115
Tel:  (617) 432-0322 (office)
        (617) 432-0323 (lab)
Fax: (617) 432-1639
Email:  cweitz at hms.harvard.edu<mailto:cweitz at hms.harvard.edu>


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