[3dem] Senior Microscopist/Microscopes and Facility Manager, Nanoimaging Services, Woburn (MA)

[Giovanna Scapin]

Nanoimaging Services is the global leader in cryo transmission electron
microscopy services. Our services are designed to meet the specific
imaging, analysis and documentation requirements of the pharmaceutical,
biotechnology and nanotechnology industries.



NIS is unique in its capability of providing high resolution protein
structure determination services by CryoEM, using advanced in-house
microscopes. We work with a broad client base through access modes that
include fee-for-service, bulk microscope access and training-centered
partnership programs to deliver best-in-class results for drug discovery
and development.



In joining NIS, you will become a key member of a highly talented,
dedicated team of scientists pushing boundaries in structural biology:

·       to deliver exceptional value to our clients

·       to drive CryoEM adoption

·       to enable expanded structural support for the most challenging of
targets in drug discovery and development



We are currently looking for a *Senior Microscopist / Microscopes &
Facility manager* at our Woburn, MA location.


Interested individuals are encouraged to send a resume, with a cover
letter, containing information on their education, employment history, a
minimum of three references, and any other relevant achievements to
*Woburn at nanoimagingservices.com
<Woburn at nanoimagingservices.com>*


Job description:



Responsibilities include but are not limited to:



*As senior microscopist: *

- Electron microscopy data collection, analysis, and pre-processing (sample
intake, sample preparation, grid preparation, grid screening and
evaluation, setting up data collection, setting up data pre-processing).
All steps need to be documented and reported following established
protocols and using the internal database.

- Training, assisting and overseeing junior microscopists

- Training members of our partnerships program in sample preparation and
data collection and processing



*As Microscopes & Facility manager:*

- Responsible for keeping the microscopes in the best possible working
condition - checking on data quality/alignments when needed, interfacing
and alerting Service engineers when there may be possible issues well ahead
of time when possible, scheduling PMs, ensure the facility is stocked with
various microscopy needs

- Proactively design and implement improvements in the workflow to improve
speed, quality and reliability of data collection.

- Maintaining a very good relationship with the Service engineers and
keeping organized with the NIS IT department to keep communication open and
information on hand when needed

- Work closely with the Chief Scientist for microscopes time slot
scheduling and management

- Providing operational support to the facility, including, but not limited
to overseeing and maintaining all ancillary equipment (DH room,
vitrification robots, analytical instruments, BSL2 cabinet, freezers etc),
overseeing junior lab technicians, supporting laboratory organization, and
ensuring compliance with documentation requirements.

- Planning and executing facility updates and addressing future needs



 *Minimum experience:*



- A Master or PhD in Structural Biology, Biology, Chemistry, Biochemistry,
Biophysics, Bioengineering or a related area in life sciences

- A minimum of 3-5 years of experience in cryoEM analysis of biological
molecules;

- Hands-on experience in operation of Vitrobot, manual plunger and/or other
related equipment in biological electron microscopy;

- Hands-on experience in operation of electron microscopes for image
collection preferably Titan Krios, Glacios and Tecnai microscopes

- Experience in high resolution cryoEM;

- Hands-on experience in usage of cryoEM software for automated image
collection;

- Experience managing a lab/facility a plus;

- Skills in working and communicating with colleagues at all levels;

- Ability in working on multiple challenging tasks in a rapidly-paced
environment
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