[3dem] Postdocs in CryoEM/ET of viruses and cells

[John Briggs]

CryoEM/ET Postdoc positions: Structure and assembly of viruses; Structures and mechanisms in membrane trafficking.

Structural studies of enveloped viruses
Projects are available addressing the structure and the assembly mechanisms of enveloped viruses including influenza A, HIV-1 and SARS-CoV-2, primarily by applying cryo-electron microscopy and tomography methods. You should have a PhD in a relevant subject (Biophysics, virology, computational sciences, structural biology or similar), relevant experience in virology and/or structural biology, and a strong interest in virus structure. Expertise in cryo-electron microscopy would be an advantage.

Mechanisms of membrane trafficking vesicle assembly
Projects are available studying the structures, the assembly mechanisms, and the regulation of the protein coats of membrane trafficking vesicles, in collaboration with David Owen (CIMR, University of Cambridge). You will make use of biochemical techniques (protein production and characterisation, lipid work, in-vitro reconstitution etc) and structural techniques (primarily cryo-electron microscopy and cryo-electron tomography, crystallography if appropriate). You should have a PhD in a relevant subject (biochemistry, biophysics, cell biology, structural biology or similar), relevant experience in biochemistry and/or structural biology, and a strong interest in cellular mechanisms and protein structure.

>From September, we will be located at the Max Planck Institute of Biochemistry in the Munich area. The institute is in a beautiful area, is vibrant and international, and has outstanding facilities for cryo-electron tomography and image processing.

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