[3dem] Genentech Postdoctoral Fellowship – Structural Biology, Matsumoto Lab

[Marissa Matsumoto]

Dear Colleagues,

My lab, within the Structural Biology Department at Genentech, is seeking
an innovative Postdoctoral Fellow to pursue engineering and structural
characterization of immunoglobulins and their interactions with various
cellular receptors and antigens. The Postdoctoral Fellow will use protein
engineering paired with X-ray crystallography and/or cryo-electron
microscopy (cryo-EM) to explore various immunoglobulin formats for
technology development and potential therapeutic applications. He/she will
structurally characterize complexes of immunoglobulins with their receptors
to elucidate the molecular mechanisms of recognition and understand
structure-function relationships. The successful candidate will spearhead
all aspects of his/her projects including antibody engineering, protein
purification, biophysical characterization, and structure determination.
Our department has state-of-the-art crystallography and cryo-EM facilities
along with directed evolution platforms for protein engineering. This is a
unique Postdoctoral Fellowship opportunity to pursue cutting-edge
technology development and publication-oriented basic research in a highly
collaborative, industrial setting.

The successful candidate will be a highly motivated and detail-oriented
researcher, driven to solve complex scientific problems, and able to work
both independently and in a collaborative environment. Strong oral and
written communication skills are required. Candidates must have a Ph.D. in
structural biology, biochemistry, molecular biology, or a related field.
Expertise in protein purification, biophysical characterization, and
structure determination by X-ray crystallography and/or single-particle
cryo-EM is required, as evidenced by a strong record of first-author
publications in top peer-reviewed journals. Experience in protein
engineering and directed evolution techniques, such as phage display, along
with biophysical characterization methods for protein-protein interactions,
such as surface-plasmon resonance (SPR) or bio-layer interferometry (BLI),
are a plus.

For more information on the Matsumoto Lab, please visit:
https://urldefense.com/v3/__https://www.gene.com/scientists/our-scientists/marissa-matsumoto__;!!Mih3wA!Tb16Eit9cjdyjn7v5wZeZIE7ym_U65B4iJO-gerjj1GMq2vjnG9ppGrQ8ReSvm_9LA$ 

For more information on the Genentech Postdoctoral Program, please visit:
https://urldefense.com/v3/__http://www.gene.com/careers/academic-programs/postdocs__;!!Mih3wA!Tb16Eit9cjdyjn7v5wZeZIE7ym_U65B4iJO-gerjj1GMq2vjnG9ppGrQ8RdyhgcebA$ 
Interested applicants should apply here:
https://urldefense.com/v3/__https://www.gene.com/careers/detail/202010-127016/Postdoctoral-Fellow-Oe-Structural-Biology-Matsumoto-Lab__;!!Mih3wA!Tb16Eit9cjdyjn7v5wZeZIE7ym_U65B4iJO-gerjj1GMq2vjnG9ppGrQ8RcqlBw65Q$ 


Best regards,
Marissa Matsumoto

-- 
--------------------------------------
Marissa L. Matsumoto, Ph.D.
Senior Scientist
Department of Structural Biology
Genentech, Inc. | 1 DNA Way, MS33 | South San Francisco, CA 94080
office: (650) 225-4711 | cell: (650) 228-4806
matsumoto.marissa at gene.com
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