<div dir="ltr"><div class="gmail_default" style="font-family:arial,helvetica,sans-serif"><div class="gmail_default" style="font-family:Arial,Helvetica,sans-serif"><font face="arial, sans-serif">Dear Colleagues, </font></div><div class="gmail_default" style="font-family:Arial,Helvetica,sans-serif"><font face="arial, sans-serif"><br></font></div><div class="gmail_default" style="font-family:Arial,Helvetica,sans-serif"><p class="MsoNormal" style="margin:0in 0in 13pt;line-height:16pt"><font face="arial, sans-serif"><span style="letter-spacing:-0.15pt">My lab, within the Structural Biology Department at Genentech, is seeking an innovative Postdoctoral Fellow to </span>pursue engineering and structural characterization of immunoglobulins and their interactions with various cellular receptors and antigens. The Postdoctoral Fellow will use protein engineering paired with X-ray crystallography and/or cryo-electron microscopy (cryo-EM) to explore various immunoglobulin formats for technology development and potential therapeutic applications. He/she will structurally characterize complexes of immunoglobulins with their receptors to elucidate the molecular mechanisms of recognition and understand structure-function relationships. The successful candidate will spearhead all aspects of his/her projects including antibody engineering, protein purification, biophysical characterization, and structure determination. Our department has state-of-the-art crystallography and cryo-EM facilities along with directed evolution platforms for protein engineering. This is a unique Postdoctoral Fellowship opportunity to pursue cutting-edge technology development and publication-oriented basic research in a highly collaborative, industrial setting.</font></p><p class="MsoNormal" style="margin:0in 0in 13pt;line-height:16pt"><font face="arial, sans-serif"><span style="letter-spacing:-0.15pt">The successful candidate will be a highly motivated and detail-oriented researcher, driven to solve complex scientific problems, and able to work both independently and in a collaborative environment. Strong oral and written communication skills are required. Candidates must have a Ph.D. in structural biology, biochemistry, molecular biology, or a related field. Expertise in protein purification, biophysical characterization, and structure determination by X-ray crystallography and/or single-particle cryo-EM is required, as evidenced by a strong record of first-author publications in top peer-reviewed journals. Experience in protein engineering and directed evolution techniques, such as phage display, along with biophysical characterization methods for protein-protein interactions, such as surface-plasmon resonance (SPR) or bio-layer interferometry (BLI), are a plus.</span><br></font></p></div><div style="font-family:Arial,Helvetica,sans-serif"><p class="MsoNormal" style="margin:0in 0in 13pt;line-height:16pt"><span style="letter-spacing:-0.15pt"><font face="arial, sans-serif">For more information on the Matsumoto Lab, please visit: <a href="https://urldefense.com/v3/__https://www.gene.com/scientists/our-scientists/marissa-matsumoto__;!!Mih3wA!Tb16Eit9cjdyjn7v5wZeZIE7ym_U65B4iJO-gerjj1GMq2vjnG9ppGrQ8ReSvm_9LA$" target="_blank" style="color:blue">https://www.gene.com/scientists/our-scientists/marissa-matsumoto</a></font></span></p><p class="MsoNormal" style="margin:0in 0in 13pt;line-height:16pt"><span style="letter-spacing:-0.15pt"><font face="arial, sans-serif">For more information on the Genentech Postdoctoral Program, please visit: <a href="https://urldefense.com/v3/__http://www.gene.com/careers/academic-programs/postdocs__;!!Mih3wA!Tb16Eit9cjdyjn7v5wZeZIE7ym_U65B4iJO-gerjj1GMq2vjnG9ppGrQ8RdyhgcebA$" target="_blank" style="color:blue">http://www.gene.com/careers/academic-programs/postdocs</a></font></span></p></div><div style="font-family:Arial,Helvetica,sans-serif"><div class="gmail_default"><font face="arial, sans-serif">Interested applicants should apply here: </font></div><div class="gmail_default"><font face="arial, sans-serif"><a href="https://urldefense.com/v3/__https://www.gene.com/careers/detail/202010-127016/Postdoctoral-Fellow-Oe-Structural-Biology-Matsumoto-Lab__;!!Mih3wA!Tb16Eit9cjdyjn7v5wZeZIE7ym_U65B4iJO-gerjj1GMq2vjnG9ppGrQ8RcqlBw65Q$" target="_blank">https://www.gene.com/careers/detail/202010-127016/Postdoctoral-Fellow-Oe-Structural-Biology-Matsumoto-Lab</a></font></div></div></div><div class="gmail_default" style="font-family:arial,helvetica,sans-serif"><br></div><div class="gmail_default" style="font-family:arial,helvetica,sans-serif"><br></div><div class="gmail_default" style="font-family:arial,helvetica,sans-serif">Best regards,</div><div class="gmail_default" style="font-family:arial,helvetica,sans-serif">Marissa Matsumoto</div><div><br></div>-- <br><div dir="ltr" class="gmail_signature" data-smartmail="gmail_signature"><div dir="ltr"><div><div dir="ltr"><div><div dir="ltr"><div dir="ltr">--------------------------------------</div><div dir="ltr"><font face="arial, helvetica, sans-serif">Marissa L. Matsumoto, Ph.D. </font></div><div dir="ltr"><span style="font-size:12.8px"><font face="arial, helvetica, sans-serif">Senior Scientist </font></span></div><div dir="ltr"><span style="font-size:12.8px"><font face="arial, helvetica, sans-serif">Department of Structural Biology</font></span><div style="font-size:12.8px"><font face="arial, helvetica, sans-serif">Genentech, Inc. | <span style="font-size:12.8px">1 DNA Way, MS33 | </span><span style="font-size:12.8px">South San Francisco, CA 94080</span></font></div><div style="font-size:12.8px"><font face="arial, helvetica, sans-serif">office: (650) 225-4711 | <span style="font-size:12.8px">cell: (650) 228-4806</span></font></div><div style="font-size:12.8px"><a href="mailto:matsumoto.marissa@gene.com" target="_blank"><font face="arial, helvetica, sans-serif">matsumoto.marissa@gene.com</font></a></div><div><br></div></div></div></div></div></div></div></div></div>