[3dem] Senior Scientist position in Cryo-EM

Natalia de Val natalia.deval at gmail.com
Tue Aug 21 10:44:07 PDT 2018

Posted on behalf of Professor Roll-Mecak:
The laboratory of Professor  Roll-Mecak is currently seeking an outstanding
individual to join their team as Senior Scientist in Cryo-Electron
Microscopy at the National Institute of Neurological Disorders and Stroke
in Bethesda. The successful candidate will join a multidisciplinary group
with expertise in molecular biology, protein biochemistry, X-Ray
crystallography and high-resolution fluorescence microscopy with a mission
to provide molecular insights into important cytoskeletal regulators. The
lab has regular access to a state-of-the art cryo-EM facility which
includes a Titan Krios with a K2 direct electron detector with energy
filter and will soon add a 200 kV Talos Arctica.

The Senior Scientist will:

   - Bring innovative structural biology technologies, with a focus on
   cryo-EM as a method for novel protein structure determination
   - Design and conduct experiments for all aspects of structure
   determination by Cryo-EM, including grid preparation, data collection and
   processing and 3-D model building.
   - Work closely with molecular biologists, protein scientists,
   biophysicists as part of an integrated structural biology effort
   - Interface with the central trans-NIH cryo-EM facility for optimal data
   collection strategies
   - Training, assisting and overseeing scientists in the group in sample
   preparation for cryo-EM, data collection and image processing
   - Contribute to the strategic planning of our group in cryo-EM


   - A minimum of a Ph.D. or equivalent is required
   - Postdoctoral experience in structural biology or related field is
   - A minimum of 3 years of research experience in single particle
   cryo-electron microscopy in industry or an academic institution is required
   - Deep scientific expertise in structural biology and high-resolution
   structure determination is required
   - Strong record of external publications and presentations is required
   - Experience in scientific programming and ability to work with the
   latest relevant software packages
   - Experience in cryo-electron tomography a plus
   - Skills in working and communicating with scientists at all levels

Salary and benefits are generous and commensurate with research experience
and accomplishments. The DC area is a great place to live with access to
many cultural and outdoors activities. NINDS offers a rich and diverse
scientific environment and the resources on campus are unparalleled. More
information can be found at: https://neuroscience.nih.gov/ninds/rm_lab/
and https://neuroscience.nih.gov/ninds/Home.aspx

To apply: Please send a cover letter, curriculum vitae, bibliography, a
one-page statement of research experience relevant to this position and the
names of three references to Dr. Antonina Roll-Mecak ( Antonina at mail.nih.gov )
Applications will be considered until December 1, 2018.


Antonina Roll-Mecak

Senior Investigator and Chief

Cell Biology and Biophysics Unit

Porter Neuroscience Research Center


National Institutes of Health

Administrative contact: Karen Kendrick; Ph: 301-451-9223; Email:
Karen.kendrick at nih.gov <Katie.tipton at nih.gov>

Lab website: https://neuroscience.nih.gov/ninds/RM_Lab/
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