[3dem] JOB POSTING: Senior Scientist II, Protein Purification, Discovery, Global Biologics

Serysheva, Irina I Irina.I.Serysheva at uth.tmc.edu
Wed Aug 8 07:53:52 PDT 2018

Dear All,

Here is a job posting on behalf of Abbvie Bioresearch Center, Global Biologics – Protein Sciences
USA, Massachusetts, Worcester<https://abbvie.referrals.selectminds.com/jobs/4049/other-jobs-matching/location-only>


Job Description

The Global Protein Sciences (GPS) Group is seeking a highly motivated Senior Scientist to join its Protein Purification Group at AbbVie Bioresearch Center in Worcester, MA. As a member of the group, the candidate will be responsible for working in cross functional teams with other scientists in various therapeutic areas as well as the Biologics generation group in Worcester to advance the pipeline. The successful candidate will have experience in protein engineering and purification of immunogens and therapeutics with a good understanding of technologies for generating proprietary biotherapeutics.

Key Responsibilities Include:

•Design alternate therapeutic formats (Multi-specifics, Non-Ig Scaffolds etc.), fusion proteins, immunogens from concept using computational tools (Rosetta/pymol/others) and execute through experimental production and characterization

•Enable progression of targets through the pipeline with appropriate reagents that elucidate a mechanistic understanding of target biology

•Design, express, purify and characterize soluble and membrane protein targets with enhanced expression and stability enabling functional studies and antibody discovery

•Purify integral membrane proteins/complexes for querying target biology, therapeutic development and structural studies.

•Introduce and lead innovative science enabling publication and external presentations

Qualifications •BS, MS or PhD with a strong foundation in biochemistry, protein purification, structural biology, and at least 12-14+ (BS), 10-12+ (MS) or 4-6+ (PhD) years of post-graduate experience in protein design and purification

•Significant research experience as demonstrated by a track record of publications and scientific accomplishments

•Experience with commercially available automated purification systems

•Experience with expression and purification from various host expression systems such as mammalian (HEK/CHO), insect/baculovirus and E.Coli.

•Experience in display technologies (phage, yeast) is a plus

•Demonstrated ability to work with multidisciplinary biologics groups in a fast paced discovery team setting

•Participation in project teams and effective communication with team members throughout the organization.

•Highly developed leadership skills and ability to engage collaborators across the organization

 Equal Opportunity Employer Minorities/Women/Veterans/Disabled

Principal Research Scientist

[cid:image001.png at 01D42F00.F5777860]
Abbvie Bioresearch Center
Global Biologics – Protein Sciences
100 Research Drive
Worcester, MA 01605
OFFICE    +1 508-688-3980
CELL        +1 508-847-3242
FAX         +1 508-755-3091
EMAIL  Medha.Tomlinson at abbvie.com<mailto:Medha.Tomlinson at abbvie.com>

This communication may contain information that is proprietary, confidential, or exempt from disclosure. If you are not the intended recipient, please note that any other dissemination, distribution, use or copying of this communication is strictly prohibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mail and delete it from his or her computer.
Irina I. Serysheva, Ph.D.
Associate Professor, Department of Biochemistry and Molecular Biology
Director of Structural Biology Imaging Center
McGovern Medical School
The University of Texas Health Science Center at Houston
6431 Fannin, MSB 6.210, Houston, TX 77030

Tel.: 713-500-5523 (office); 713-500-6232 (lab)
Fax: 713-500-0652
E-mail: Irina.I.Serysheva at uth.tmc.edu<mailto:Irina.I.Serysheva at uth.tmc.edu>
              irinas at bcm.edu<mailto:irinas at bcm.edu>
"Success is the ability to go from one failure to another with no loss of enthusiasm" - Sir Winston Churchill

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