[3dem] Position Open - Scientist I, Electron Microscopy

[Baxa, Ulrich (NIH/NCI) [C]]

The EM lab at the Frederick National Laboratory for Cancer Research is looking for a Scientist:


Message: Scientist I, 618013 (NCI)

FREDERICK, MD US



Apply on-line:  http://jobs.leidos.com/ShowJob/Id/529588/Scientist-I-618013-(NCI)/



The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community. A major focus of the CRTP is the NCI RAS Initiative with the goal to discover new therapeutic interventions against RAS-driven cancers. In addition, the CRTP hosts the Nanotechnology Characterization Laboratory (NCL) which performs and standardizes preclinical efficacy and toxicity testing of nanoparticles intended for cancer therapeutics and diagnostics, and the Antibody Characterization Lab (ACL) which characterizes monoclonal antibodies or other renewable affinity binding reagents for use in cancer related research. CRTP scientists also work collaboratively with intramural NCI investigators to provide research technologies and expertise.



JOB DESCRIPTION



The CCR Electron Microscopy Core has access to four transmission electron microscopes (Hitachi H-7600, Hitachi H-7650, FEI T-12 BioTwin, and FEI T-20) and two scanning electron microscopes (Hitachi S-3000N and S-4500). The Scientist I will: 1) maintain the FEI T-12 and keep it at optimal performance, 2) perform sample preparation for imaging of tissue, cells, organelles, viruses and molecules with a variety of techniques including plastic embedding and sectioning, high-pressure freezing, negative stain, and electron tomography, and 3) help core users with their microscopy projects and perform training of new microscope users.



BASIC QUALIFICATIONS

PhD in biochemistry, structural biology, protein biochemistry, crystallography, or in a related discipline from an accredited college or university appropriate to biomedical research, or eight (8) years experience in lieu of degree. Foreign degrees must be evaluated for U.S. Equivalency. No experience required beyond degree. Proficiency in biological and/or material sample preparation for electron microscopy. Proficiency in the use and maintenance of transmission electron microscopes. Strong research background and publication record. Must be able to communicate well with service engineers for equipment on service contracts





PREFERRED QUALIFICATIONS

Experience in correlative light/electron microscopy Experience in immuno-electron microscopy Knowledge of tomography and related image processing Experience with cryo EM applications, in particular high pressure freezing, freeze substitution, and cryo-sectioning Knowledge of digital image processing and analysis



Apply on-line:  http://jobs.leidos.com/ShowJob/Id/529588/Scientist-I-618013-(NCI)/



Leidos Overview:

Leidos is an applied solutions company focused on markets that are seeing converging business and technological trends, and address basic, enduring human needs: defense and national security, health and life sciences, and energy, engineering and infrastructure. The Company's approximately 20,000 employees serve customers in the U.S. Department of Defense, the intelligence community, the U.S.

Department of Homeland Security, other U.S. Government civil agencies and commercial health and engineering markets. Leidos is an Equal Opportunity Employer.



Contact: kathryn.burke at nih.gov<mailto:kathryn.burke at nih.gov>


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