[3dem] Workshop on Cryo-EM Modeling Based on X-ray Crystallography, January 8-10, 2014, Urbana, Illinois

[TCBG Workshops]

The Theoretical and Computational Biophysics Group (www.ks.uiuc.edu) in 
collaboration with  Forschungszentrum Julich announces a

"Workshop on Cryo-EM Modeling Based on X-ray Crystallography"

to be held January 8-10, 2014, at the Beckman Institute in Urbana, Illinois.

The purpose of the workshop is to present recent developments in the 
area of cryo-EM guided modeling of macromolecular structures and to 
provide the participants with simple, practical experience in using 
these methods. In particular, the workshop will cover NAMD and VMD, 
Molecular Dynamics Flexible Fitting (MDFF) and DireX. Relevant physical 
concepts, mathematical algorithms, and computational methods will be 
introduced, including molecular dynamics simulation, de novo structure 
determination based on cryo-EM maps, deformable elastic networks, 
stereochemical validation of proteins and nucleic acids, and quality 
checks of fitted structures. Specific examples utilizing the MDFF and 
DireX programs will be introduced and discussed in detail. Participants 
are invited and encouraged to bring their own molecular modeling 
problems to the workshop, for group discussion of how to address those 
problems via a computational approach. The workshop will be presented by 
members of the Theoretical and Computational Biophysics Group from the 
University of Illinois at Urbana-Champaign and members of the 
Computational Structural Biology Group from the Forschungszentrum Julich.

The workshop is designed for researchers in the fields of cryo-electron 
microscopy who seek to fit molecular structure from x-ray 
crystallography into cryo-EM density maps, and computational 
biophysicists who are interested in cryo-EM guided modeling method 
development. Advanced lecture sessions will be followed by extended 
discussion periods between lecturers and participants and laboratory 
time in which students will be able to work on hand-on tutorials and 
their own molecular modeling projects. Enrollment is limited to 20 
participants. The workshop will be held January 8-10, 2014, in Urbana, 
Illinois. All participants are required to bring their own laptop for 
use in the workshop training sessions. Participants must arrange and pay 
for their own travel; see website for information on accommodations, 
registration fees and important dates.

http://www.ks.uiuc.edu/Training/Workshop/mdff/

We look forward to receiving your application!

Regards,
The TCBG Workshop Team