[3dem] relion-1.2 release

[Sjors Scheres]

Dear colleagues,

We have now released version 1.2 of our single-particle refinement 
program RELION. RELION employs an empirical Bayesian approach to infer 
model parameters from the data, so that objective and high-quality 
reconstructions are obtained with minimal user intervention. We recently 
used this program to obtain near-atomic resolution ribosome maps from 
~30k particles (http://dx.doi.org/10.7554/eLife.00461).

Apart from bug fixes and code optimisation, release 1.2 has two new main 
features:
1) a movie-processing procedure (which we used to process the DDD-movies 
in the eLife paper mentioned above)
2) a semi-automated post-processing procedure (for improved resolution 
estimates after masking, see Shaoxia Chen et al, Ultramicroscopy in 
press, MTF correction and B-factor sharpening)

More details and download instructions are on the RELION wiki at 
http://www2.mrc-lmb.cam.ac.uk/relion. Please note we use the CCP-EM 
mailing list (http://www.jiscmail.ac.uk/CCPEM) as a forum for 
RELION-related questions, bug reports, etc.

Hoping RELION-1.2 will be useful in your research,
Sjors

PS: A special thanks to all those involved in beta-testing. Please 
re-install the official 1.2 release if you have previously worked with a 
pre-release version.

-- 
Sjors Scheres
MRC Laboratory of Molecular Biology
Francis Crick Avenue, Cambridge Biomedical Campus
Cambridge CB2 0QH, U.K.
tel: +44 (0)1223 267061
http://www2.mrc-lmb.cam.ac.uk/groups/scheres