[3dem] permanent researcher position in 3D cryo-EM in Paris

[Slavica Jonic]

Dear Colleagues:

We are searching for a candidate for a permanent researcher position in 
3D cryo-electron microscopy (cryo-EM) of macromolecular assemblies to 
join our group. There is currently an opportunity at the French national 
research center CNRS for candidates with an interdisciplinary profile 
and the deadline for the CNRS on-line application is *January 6, 2011*. 
The candidates experienced in the development of methods for image 
analysis as well as French and non-French-speaking candidates are 
strongly encouraged to apply.Please e-mail us as soon as possible if you 
are interested in joining our group by applying for this opportunity. We 
will select the candidate best matching the expected profile and will 
help him/her to prepare the application for this opportunity. The 
application of the selected candidate will be strongly supported by the 
direction of our unity.

We are "Structure of Macromolecular Assemblies" group at the IMPMC 
(Institut de Minéralogie et de Physique des Milieux Condensés) that is a 
mixed unity composed of the personnel from the CNRS, the University 
Pierre et Marie Curie -- Paris 6, and the University Denis Diderot-Paris 
7. Our research activities include high-resolution structure 
determination by single-particle cryo-EM and electron crystallography, 
and development of new methodologies for single-particle image analysis.

Instrumentation includes a JEOL 200kV FEG (JEM-2100F) and a JEOL 200kV 
LaB6 (JEM-2100) featuring cryo capabilities, energy filtration, STEM, 
large 2K and 4K Gatan CCDs, two Digitizer Nikon Coolscan 8000 ED and 
9000 ED, a film-handling robot for Nikon Digitizer, an automated 
cryo-plunger with a controlled environment and an AMD Opteron cluster. A 
ZEISS Ultra 55 FEG SEM and a ZEISS Neon 40Esb FEG FIB are also present 
at our laboratory. The laboratory possess the equipment necessary for 
expression and purification of soluble and membrane proteins.

We are currently working on Phosphorylase Kinase, a large macromolecular 
complex involved in glycogenolysis and also on translation 
pre-initiation complexes in collaboration with other experimental groups.
We have also strong interest in membrane protein structure such as 
potassium channels. Our current research also involves development of 
novel methodologies for 4D single-particle analysis by taking advantage 
of conformational heterogeneity present in a sample.

You can e-mail us at (*slavica.jonic at impmc.upmc.fr*) or 
(*catherine.venien at impmc.upmc.fr*) for further details.

Best wishes.

-- 
Dr Slavica JONIC, CR1 CNRS
Institut de Minéralogie et de Physique des Milieux Condensés (IMPMC)
UMR 7590 CNRS-Paris 6-Paris 7-IPGP-IRD
Campus Jussieu
Tour 23 - Couloir 22/23 - 5e étage - Bureau 7
Case courrier 115
4 Place Jussieu
75252 Paris Cedex 05
France

Tel: +33 1 44 27 72 05
Fax: +33 1 44 27 37 85
E-mail: Slavica.Jonic at impmc.upmc.fr

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