[3dem] Cooled & Humidified Enclosure for Manual Grid Preparation - GraVitri 4°C Module
Benjamin Apker
benjamin.apker at mitegen.com
Tue Sep 8 09:31:08 PDT 2026
Dear 3DEM community,
Following our initial release of the modular GraVitri Plunge Cooler Series
for manual grid preparation, we are excited to introduce the *GraVitri 4°C
Module*. This active temperature-controlled enclosure is designed to
provide precise environmental control for researchers working with
temperature-sensitive or fragile biological specimens.
*GraVitri 4°C Module Technical Highlights:*
-
*Active Environmental Control: *Maintains the sample environment
anywhere from 4°C to ambient temperatures, and integrates a humidity sensor
and forced-convection humidification system to significantly slow
evaporation during the blotting process.
-
*Probe Cold Sensitivity*: Allows temperature-resolved studies with +/-
1C accuracy for thermo-responsive samples, like chilling injury sensitive
cells for cryoET or signal transduction proteins like TRMP8 for single
particle cryoEM.
-
*Mitigation of Interface Artifacts:* Stabilizes temperature-sensitive
complexes to aid in cold-sensitivity characterization and reduces air-water
interface damage during single-particle analysis workflows.
-
*Drop-In Modularity:* Functions as a direct, swappable accessory for
existing GraVitri manual plunge coolers, allowing labs to continuously
build upon their system as experimental needs change.
Technical details, specifications, and documentation are available on the
product page:
https://urldefense.com/v3/__https://www.mitegen.com/plunge-cooler-series/gravitri-plunge-cooler-series-4c-module/__;!!Mih3wA!AHVtpaQIBF0LuXYg6yF_aTfosdvdD_2ySn0hG-NZIpZYPTvarSGjn817i3omC2_e503InQlxPWy_EjN0v-eqUDQL_Rjm$
We welcome community feedback and look forward to supporting your
workflows. For technical questions or to discuss your specific sample prep
challenges, please feel free to reach out directly.
Best regards,
Ben
--
Benjamin Apker
Chief Executive Officer
MiTeGen
95 Brown Road
MS 1034, Suite 124
Ithaca, NY 14850
office: +1-607-266-8877
fax: +1-607-697-0400
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