[3dem] Cooled & Humidified Enclosure for Manual Grid Preparation - GraVitri 4°C Module

Benjamin Apker benjamin.apker at mitegen.com
Tue Sep 8 09:31:08 PDT 2026


Dear 3DEM community,

Following our initial release of the modular GraVitri Plunge Cooler Series
for manual grid preparation, we are excited to introduce the *GraVitri 4°C
Module*. This active temperature-controlled enclosure is designed to
provide precise environmental control for researchers working with
temperature-sensitive or fragile biological specimens.

*GraVitri 4°C Module Technical Highlights:*


   -

   *Active Environmental Control: *Maintains the sample environment
   anywhere from 4°C to ambient temperatures, and integrates a humidity sensor
   and forced-convection humidification system to significantly slow
   evaporation during the blotting process.
   -

   *Probe Cold Sensitivity*: Allows temperature-resolved studies with +/-
   1C accuracy for thermo-responsive samples, like chilling injury sensitive
   cells for cryoET or signal transduction proteins like TRMP8 for single
   particle cryoEM.
   -

   *Mitigation of Interface Artifacts:* Stabilizes temperature-sensitive
   complexes to aid in cold-sensitivity characterization and reduces air-water
   interface damage during single-particle analysis workflows.
   -

   *Drop-In Modularity:* Functions as a direct, swappable accessory for
   existing GraVitri manual plunge coolers, allowing labs to continuously
   build upon their system as experimental needs change.

Technical details, specifications, and documentation are available on the
product page:

https://urldefense.com/v3/__https://www.mitegen.com/plunge-cooler-series/gravitri-plunge-cooler-series-4c-module/__;!!Mih3wA!AHVtpaQIBF0LuXYg6yF_aTfosdvdD_2ySn0hG-NZIpZYPTvarSGjn817i3omC2_e503InQlxPWy_EjN0v-eqUDQL_Rjm$ 

We welcome community feedback and look forward to supporting your
workflows. For technical questions or to discuss your specific sample prep
challenges, please feel free to reach out directly.

Best regards,
Ben

-- 
Benjamin Apker
Chief Executive Officer
MiTeGen

95 Brown Road
MS 1034, Suite 124
Ithaca, NY 14850
office: +1-607-266-8877
fax:    +1-607-697-0400
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