[3dem] Postdoctoral Research Associate Position in Structural Biology of Chromosome Segregation

[Jeyaprakash Arulanandam]

Dear all,

We are looking for a highly motivated postdoctoral candidate with cryoEM training to join us (the JP lab, https://urldefense.com/v3/__http://biology.ed.ac.uk/jeyaprakash__;!!Mih3wA!EG_CTI8HxjPP7zXhgZQtQkJCARNedpMHQGNP5ARsg7H51HH-aRmTKi3yqN12tO_zw6-vxCJ_OdZ-M1JFvxg8J63cEFc7WJc$ ) to discover non-canonical mechanisms of genome transfer in a clinically relevant human fungal pathogen, Cryptococcus neoformans, as part of a Wellcome Discovery Award-funded research program.

Cryptococcus neoformans is an understudied environmental yeast, designated the most critical priority human fungal pathogen by the World Health Organisation (WHO).  Mostly immunocompromised patients succumb to Cryptococcal infections, causing ~147,000 deaths in AIDS patients. This will be a highly interactive and collaborative study with the groups of Prof. Hardwick (https://urldefense.com/v3/__https://biology.ed.ac.uk/hardwick__;!!Mih3wA!EG_CTI8HxjPP7zXhgZQtQkJCARNedpMHQGNP5ARsg7H51HH-aRmTKi3yqN12tO_zw6-vxCJ_OdZ-M1JFvxg8J63cj1a-Yy4$ ) at the University of Edinburgh and Prof. Sanyal (https://urldefense.com/v3/__https://molecularmycologylab.wixsite.com/kaustuv__;!!Mih3wA!EG_CTI8HxjPP7zXhgZQtQkJCARNedpMHQGNP5ARsg7H51HH-aRmTKi3yqN12tO_zw6-vxCJ_OdZ-M1JFvxg8J63cmt6r6J4$ ) at JNCASR, Bengaluru.

The project will involve dissecting the mechanisms that regulate chromosome segregation and cell division using a range of structural biology, biochemical, and biophysical methods, complemented by yeast genetics and cell biology (in collaboration with the Profs. Hardwick and Sanyal labs). The position is initially fixed-term for 36 months and is ideally suited for ambitious, motivated, and creative individuals.

The candidate will benefit from excellent core resources, including a state-of-the-art Glacios 2 electron microscope equipped with a Falcon 4i direct detector and a Selectris-X energy filter, as well as proteomics and light microscopy facilities.

For an overview of our recent research, see: https://urldefense.com/v3/__https://doi.org/10.1126/science.ado8270__;!!Mih3wA!EG_CTI8HxjPP7zXhgZQtQkJCARNedpMHQGNP5ARsg7H51HH-aRmTKi3yqN12tO_zw6-vxCJ_OdZ-M1JFvxg8J63cRVN6yxg$ ; https://urldefense.com/v3/__https://doi.org/10.1038/s44318-025-00594-y__;!!Mih3wA!EG_CTI8HxjPP7zXhgZQtQkJCARNedpMHQGNP5ARsg7H51HH-aRmTKi3yqN12tO_zw6-vxCJ_OdZ-M1JFvxg8J63cVblnRN4$ ; https://urldefense.com/v3/__https://doi.org/10.1038/s44319-024-00183-w__;!!Mih3wA!EG_CTI8HxjPP7zXhgZQtQkJCARNedpMHQGNP5ARsg7H51HH-aRmTKi3yqN12tO_zw6-vxCJ_OdZ-M1JFvxg8J63cotO4LcQ$ ; https://urldefense.com/v3/__https://doi.org/10.1038/s41467-025-56876-w__;!!Mih3wA!EG_CTI8HxjPP7zXhgZQtQkJCARNedpMHQGNP5ARsg7H51HH-aRmTKi3yqN12tO_zw6-vxCJ_OdZ-M1JFvxg8J63ct7CK61M$ ; https://urldefense.com/v3/__https://doi.org/10.1371/journal.pgen.1011302__;!!Mih3wA!EG_CTI8HxjPP7zXhgZQtQkJCARNedpMHQGNP5ARsg7H51HH-aRmTKi3yqN12tO_zw6-vxCJ_OdZ-M1JFvxg8J63cdjFOIZ4$ ; https://urldefense.com/v3/__https://doi.org/10.1101/2022.09.21.508923__;!!Mih3wA!EG_CTI8HxjPP7zXhgZQtQkJCARNedpMHQGNP5ARsg7H51HH-aRmTKi3yqN12tO_zw6-vxCJ_OdZ-M1JFvxg8J63cAE-nNAE$ .

Experience with single-particle Cryo-EM, protein biochemistry, and single-molecule biophysics is highly desirable.  To apply for the position, please follow the link https://urldefense.com/v3/__https://elxw.fa.em3.oraclecloud.com/hcmUI/CandidateExperience/en/sites/CX_1001/job/13917__;!!Mih3wA!EG_CTI8HxjPP7zXhgZQtQkJCARNedpMHQGNP5ARsg7H51HH-aRmTKi3yqN12tO_zw6-vxCJ_OdZ-M1JFvxg8J63cR3KvAmw$ .  Closing date 31 March 2026.

Informal enquiries from prospective candidates with their CV and a statement describing their research experience, scientific interest, career goals, and motivation are encouraged: ajeyapra at ed.ac.uk<mailto:ajeyapra at ed.ac.uk>

Best regards, JP

Prof. A. Jeyaprakash Arulanandam
Personal Chair of Structural Cell Biology
Co-Head, Institute of Cell Biology
Michael Swann Building
University of Edinburgh
Kings Buildings
Max Born Crescent
Edinburgh EH9 3BF
UK
Phone: +44 131 6507113
Email: ajeyapra at ed.ac.uk<mailto:ajeyapra at ed.ac.uk>
Web: JP lab, UoE<https://urldefense.com/v3/__http://jeyaprakash.bio.ed.ac.uk/__;!!Mih3wA!EG_CTI8HxjPP7zXhgZQtQkJCARNedpMHQGNP5ARsg7H51HH-aRmTKi3yqN12tO_zw6-vxCJ_OdZ-M1JFvxg8J63cQYglWm8$ >
Gene Center and Department of Biochemistry
Ludwig-Maximilian-Universität München
Feodor-Lynen Straße 25
81377 Munich
Germany
Room: A4.68
Phone: +49 (0)89 2180 76962
Email: jparul at genzentrum.lmu.de<mailto:jparul at genzentrum.lmu.de>
Web: JP lab, GCM-LMU<https://urldefense.com/v3/__https://www.genzentrum.uni-muenchen.de/research-groups/arulanandam/index.html__;!!Mih3wA!EG_CTI8HxjPP7zXhgZQtQkJCARNedpMHQGNP5ARsg7H51HH-aRmTKi3yqN12tO_zw6-vxCJ_OdZ-M1JFvxg8J63c6vB1FC0$ >

The University of Edinburgh is a charitable body, registered in Scotland, with registration number SC005336. Is e buidheann carthannais a th’ ann an Oilthigh Dhùn Èideann, clàraichte an Alba, àireamh clàraidh SC005336.
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