[3dem] 4th Practical Workshop on Helical Symmetry

[Leandro F. Estrozi]

Dear EM community,

This is a quick reminder about the upcoming workshop on Helical Symmetry 
Determination, which will take place online from August 3rd to 7th, 2026.

Are you currently working on a helical dataset but struggling to 
determine its symmetry, or symmetries? Are you dealing with strong 
heterogeneity in filament types and unsure how to proceed? This workshop 
may be for you.

The application deadline is July 1st. Please see all details below.

Best regards,

Ambroise & Leandro


On 5/29/26 16:44, Leandro F. Estrozi wrote:
> *Dear EM (Helical Assemblies Interested) Community,*
>
> We are pleased to announce the fourth edition of the Grenoble 
> practical workshop focused on the determination of helical symmetry in 
> biological polymers imaged by cryo-EM. The workshop will take place 
> *online from August 3rd to 7th, 2026*.
>
> Please note that due to specific procedural requirements, *projects 
> involving amyloids or microtubules will not be accepted*.
>
> As in previous editions, we are honored to welcome a distinguished 
> speaker: *Ed Egelman*, whose expertise will greatly enrich our 
> discussions.
>
> Determining helical parameters continues to be a major challenge for 
> many researchers. This workshop is designed to provide *practical, 
> hands-on guidance* through the complexities of this process. Topics 
> will include interpreting power spectra, analyzing 2D class averages, 
> and examining raw data to extract meaningful structural insights.
>
> While *Helixplorer* (https://urldefense.com/v3/__https://rico.ibs.fr/helixplorer/__;!!Mih3wA!HsQ2LysaOEYnhvIcfEHE7l1qiajCEOn15cWK5eUqel9otrC--AoL4Zuy-m0Np_NABStRf_juGHrz8wfb8I8dgnhJjmxy$ ) will play a 
> central role in our practical sessions, we also encourage participants 
> to explore alternative approaches to address a variety of research needs.
>
> Beyond helical parameter determination, we will also explore *broader 
> reconstruction strategies*, including managing flexible helices, 
> working with multiple symmetries, and integrating data from different 
> filament symmetries using subtraction techniques.
>
> We welcome applicants at all career stages (PhD students, postdocs, 
> senior scientists, and beyond) *who are currently working on helical 
> samples and facing structural analysis challenges*. During the 
> workshop, participants will use their own data, sharing selected raw 
> images, 2D class averages, and power spectra with the organizers. The 
> specific identity and function of your protein or filament will remain 
> confidential.
>
> To apply, please email your application (including a brief description 
> of your project and the difficulties you’re encountering, as well as 
> examples from your raw data and 2D class averages with the 
> corresponding *pixel size*) to:
>
>  *
>
>     *ambroise.desfosses at ibs.fr*
>
>  *
>
>     *leandro.estrozi at ibs.fr*
>
> *Application deadline: July 1st.*
>
> We look forward to another engaging and fruitful workshop and hope to 
> see you online in August!
>
> *Warm regards,
> *
> /Ambroise & Leandro/
>
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