[3dem] PhD position available to work on nuclear condensate structures

[Indrajit Lahiri]

Hello

We have a PhD position (https://urldefense.com/v3/__https://www.findaphd.com/phds/project/paraspeckle-condensates-in-cell-health-stress-and-disease-what-can-structural-studies-tell-us/?p197469__;!!Mih3wA!FegCo_9FG_6nMLWmHHIhPC2UbceoaCO8A7bAn9aY0w8NsYIof5j0GtVvzycmtf6rjTiLhfhLfSx3-YFcW_ocqxY$ ) available to work on a collaborative project between my group (https://urldefense.com/v3/__https://sites.google.com/sheffield.ac.uk/lahirilab/__;!!Mih3wA!FegCo_9FG_6nMLWmHHIhPC2UbceoaCO8A7bAn9aY0w8NsYIof5j0GtVvzycmtf6rjTiLhfhLfSx3-YFc2cOu0Dw$ ) and the groups of Dr. Tatyana Shelkovnikova (https://urldefense.com/v3/__https://sheffield.ac.uk/smph/people/academic/neuroscience/tatyana-shelkovnikova__;!!Mih3wA!FegCo_9FG_6nMLWmHHIhPC2UbceoaCO8A7bAn9aY0w8NsYIof5j0GtVvzycmtf6rjTiLhfhLfSx3-YFcXLl9DVM$ ) and Professor Ade Whitehouse (https://urldefense.com/v3/__https://biologicalsciences.leeds.ac.uk/molecular-and-cellular-biology/staff/156/professor-ade-whitehouse__;!!Mih3wA!FegCo_9FG_6nMLWmHHIhPC2UbceoaCO8A7bAn9aY0w8NsYIof5j0GtVvzycmtf6rjTiLhfhLfSx3-YFcmWxy_50$ ) to delineate the ultrastructures of nuclear condensates and determine how condensate dysregulation leads to diseases. 

The project will use cryo-CLEM and soft X-ray tomography for the structural work. This work will be carried out at the University of Sheffield and at eBIC. In addition to learning cutting-edge cryoEM, the student will develop skills in mammalian cell culture, RNA biology, advanced imaging and disease modelling. 

The position covers funds for UK home students only. If you are interested in the position please feel free to get in touch with me ( I.Lahiri at sheffield.ac.uk) or Tatyana (t.shelkovnikova at sheffield.ac.uk) for an informal chat. If you know someone who might be a good fit then we request you to please forward this email to them.

Thanks,
Indrajit