[3dem] High-Performance Monolayer Graphene TEM Grids for Cryo-EM Research

[曲丽敏]

Dear Colleagues,

I hope this email finds you well.

I am writing to introduce our high-performance Monolayer Graphene TEM Grids, developed by Atomface New Materials (Lianyungang) Co., Ltd. We are dedicated to providing advanced scientific consumables for the global structural biology and cryo-EM research community.

Our graphene cryo-EM grids are designed to address key challenges in specimen preparation and characterization. By utilizing our proprietary self-assembled molecular layer transfer and conformal adhesion technology, we achieve a clean and non-destructive transfer of monolayer graphene onto TEM grids.Please check the attached product presentation.

Key advantages include:

Ultra-Low Background Signal and Enhanced Resolution

With an atomic thickness of approximately 0.34 nm, monolayer graphene is nearly transparent to the electron beam, generating minimal background scattering and significantly improving image contrast while facilitating high-resolution structure determination.

Preservation of Native Sample States

Graphene grids provide a stable solid–liquid interface that prevents samples from contacting the air–water interface (AWI). This helps reduce protein adsorption, denaturation, and preferred orientation, enabling more reliable 3D reconstruction.

Exceptional Stability and Reduced Beam-Induced Motion

Benefiting from high mechanical strength and excellent electrical and thermal conductivity, graphene grids help suppress beam-induced particle motion and improve specimen stability during imaging.

Formation of Uniform Ultrathin Vitrified Ice Layers

Functionalized graphene grids promote the formation of ultrathin vitrified ice layers while enabling most protein particles to localize at the graphene–water interface, facilitating high-resolution cryo-EM structure determination.

Reduced Sample Concentration Requirements

The high affinity and efficient particle adsorption provided by graphene grids can significantly reduce the sample concentration required for grid preparation, often by up to an order of magnitude, thereby minimizing the consumption of precious biological samples.

Our products have been adopted by more than 300 research groups and facilities across over 20 countries, including leading pharmaceutical companies and teams led by Nobel Prize laureates. They have contributed to numerous high-resolution structural biology studies worldwide.

We would be delighted to support your structural biology research with our premium graphene grids. If you are interested, I would be happy to provide additional technical specifications, evaluation samples, or discuss potential collaborations.



Best Regards,
Limin







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Atomface New Materials (Lianyungang) Co., Ltd.
Name: Limin Qu          Position: Sales Vice-President
Add:Floor 4,Building 1, No. 17 Huaguoshan Avenue, Haizhou District, Lianyungang City, Jiangsu Province,China
Tel: +86-15050597133
E-mail：qulimin1987 at 126.com
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